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What is this test?

The Aspergillus fumigatus antibody test detects whether your body has produced specific antibodies (immune proteins) against Aspergillus fumigatus, a common mold/fungus found in the environment. This test is performed on cerebrospinal fluid (CSF), the clear liquid that surrounds and protects your brain and spinal cord.

Why is this test performed?

This test is used to help diagnose aspergillosis, a fungal infection caused by Aspergillus molds. When the infection affects the brain, spinal cord, or the membranes surrounding them (meninges), it is called central nervous system (CNS) aspergillosis. Your doctor may order this test if you have symptoms of a brain or spinal infection, especially if you have a weakened immune system.

How is the sample collected?

The CSF sample is collected through a procedure called a lumbar puncture, commonly known as a spinal tap. During this procedure, a healthcare provider inserts a thin needle between the bones of your lower spine to withdraw a small amount of cerebrospinal fluid. The area is numbed with local anesthetic to minimize discomfort.

What do the results mean?

Results are typically reported as 'Positive' (antibodies detected) or 'Negative' (no antibodies detected). A positive result suggests your immune system has responded to an Aspergillus fumigatus infection, which may indicate a current or recent fungal infection in the central nervous system. A negative result means no antibodies were detected, but this does not completely rule out infection—your doctor will interpret the results together with your symptoms, medical history, and other test findings.