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Free Alpha Human Chorionic Gonadotropin (α-hCG), Serum/Plasma — Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the free alpha-hCG subunit in blood; this test is often used with other markers during pregnancy screening.

Quick summary

["A free alpha-hCG blood test measures part of the hCG hormone and is usually interpreted with other prenatal screening results."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30206-7
Short code
A-HCG Free SerPl-aCnc
Synonyms
A-HCG Free SerPl-aCnc
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
5
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84702
SNOMED
275917004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures free alpha human chorionic gonadotropin, or free alpha-hCG, in serum or plasma. Alpha-hCG is one part of the hCG hormone produced during pregnancy.

Why might I need this test?

Free alpha-hCG may be ordered as part of a prenatal screening panel that also includes other hormone markers. It is generally interpreted together with the mother's age, gestational stage, ultrasound findings, and other test results.

How is the test performed?

A blood sample is collected, and the laboratory uses a specialized method to measure the amount of free alpha-hCG in the serum or plasma.

How do I prepare for the test?

Fasting is usually not required, but follow your healthcare provider's instructions. Tell the laboratory if you are pregnant or if you have recently received hormone-based fertility treatment, because these can affect hCG measurements.

Reference range

Non-pregnant: <5 mIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An abnormal free alpha-hCG result may affect the estimated risk of certain pregnancy conditions, including chromosomal differences. The result does not by itself confirm or rule out a condition and must be interpreted with the rest of the prenatal screening or diagnostic evaluation.

Short name

Free alpha-hCG

Frequently asked questions

Is free alpha-hCG the same as a standard hCG test?
No. A standard hCG test may measure total hCG, while this test specifically measures the free alpha-hCG subunit. Some laboratories also offer a free beta-hCG test, which is different.
Does an abnormal result mean the baby has a health condition?
No. An abnormal result is only one screening finding and does not establish a diagnosis. Your healthcare provider will interpret it with other prenatal test results and clinical information.
Can fertility medications affect this test?
Yes. Products containing hCG, including some fertility treatments, can raise hCG-related measurements. Inform your healthcare provider and laboratory about any recent fertility treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy