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Alpha Subunit of Human Chorionic Gonadotropin, Serum/Plasma — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of the alpha subunit of human chorionic gonadotropin in blood. This test is distinct from the intact hCG measurement commonly used in pregnancy testing.

Quick summary

["This blood test measures an alpha-hCG subunit and is interpreted along with other hCG tests and the clinical situation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27252-6
Short code
A-HCG SerPl-mCnc
Synonyms
A-HCG SerPl-mCnc
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
5
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84702
SNOMED
275917004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the concentration of the alpha subunit of human chorionic gonadotropin, or hCG, in serum or plasma. hCG is a hormone associated with pregnancy and is also produced by certain other tissues and tumors.

Why might I need this test?

A clinician may order it when evaluating or monitoring pregnancy, gestational trophoblastic disease, or certain tumors that produce hCG. It may be used alongside intact or total hCG measurements rather than as a stand-alone test.

How is the test performed?

A blood sample is collected by venipuncture, and the serum or plasma is analyzed in the laboratory to determine the concentration of the alpha hCG subunit. The result is usually reported as an amount per unit of blood volume.

How do I prepare for the test?

Fasting is generally not required, but follow any instructions from your clinician. Tell the laboratory if you are pregnant, recently pregnant, or have received an hCG injection, because these factors can affect the results and their interpretation.

Reference range

Non-pregnant: <5 mIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Alpha hCG subunit

Frequently asked questions

Is this the same as a standard pregnancy hCG test?
No. A standard quantitative pregnancy test usually measures intact hCG, while this test specifically measures the alpha subunit. Your clinician may order both for a complete evaluation.
Can a home pregnancy test determine the alpha hCG subunit?
Usually not. Home pregnancy tests are designed to detect intact hCG and generally do not provide a separate measurement of the alpha subunit.
Do I need to fast before this blood test?
Fasting is usually unnecessary unless your clinician has given different instructions. Pregnancy status and any recent hCG injections should be reported because they may influence interpretation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy