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Human Chorionic Gonadotropin (hCG), Serum/Plasma — Substance Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of human chorionic gonadotropin (hCG) in blood. It is commonly used to confirm and monitor pregnancy and may also help evaluate certain tumors.

Quick summary

["A blood hCG level can help confirm and monitor pregnancy and may provide information about certain tumors."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2109-7
Short code
A-HCG SerPl-sCnc
Synonyms
A-HCG SerPl-sCnc
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
5
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84702
SNOMED
275917004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

Human chorionic gonadotropin, or hCG, is a hormone produced during pregnancy. This blood test measures the concentration of hCG in serum or plasma.

Why might I need this test?

A serum or plasma hCG test is often used to confirm pregnancy and may be repeated to assess how a pregnancy is progressing. Your clinician may also order it when investigating or monitoring certain germ-cell or trophoblastic tumors, which can produce hCG.

How is the test performed?

A blood sample is drawn from a vein and tested in the laboratory, usually with an immunoassay. The result reports the concentration of hCG in the blood.

How do I prepare for the test?

This test usually requires no special preparation. Follow any instructions from your clinician or laboratory, and tell them if you are pregnant or could be pregnant.

Reference range

Non-pregnant: <5 mIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

In pregnancy, hCG is normally present and its pattern of rise can help clinicians assess pregnancy progression. Levels that are lower than expected or do not rise appropriately may indicate a problem such as miscarriage, ectopic pregnancy, or reduced viability. Elevated hCG outside pregnancy can occur with some ovarian, testicular, or other germ-cell tumors and is interpreted alongside the clinical findings and other tests.

Short name

hCG, Serum/Plasma

Frequently asked questions

Is this the same as a home pregnancy test?
Both detect hCG, but this test measures its concentration in a blood sample. Blood testing is often used when more precise monitoring than a home urine test is needed.
Why are hCG levels checked more than once?
Clinicians may compare repeat results to evaluate whether hCG is rising or falling as expected. The appropriate timing and interpretation depend on the clinical situation.
Can a high hCG result mean cancer?
Not by itself. Some tumors produce hCG, but high levels can also occur in pregnancy, so the result must be interpreted with symptoms, examination findings, and other tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy