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Alpha-Lactalbumin-Specific IgE, Total

Published: August 9, 2026Updated: August 16, 2026

Measures total IgE antibodies directed against alpha-lactalbumin, a protein found in cow's milk, to help evaluate possible milk-protein sensitization.

Quick summary

["An elevated result may indicate sensitization to alpha-lactalbumin but must be interpreted with your symptoms and other allergy testing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61213-5
Short code
A-Lactalb IgE/IgE total %
Synonyms
A-Lactalb IgE/IgE total %
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This blood test measures IgE antibodies directed against alpha-lactalbumin, a milk protein. These antibodies are part of the immune response that can occur with cow's-milk-protein allergy.

Why might I need this test?

Your clinician may order this test when you have symptoms such as hives, swelling, vomiting, wheezing, or digestive problems after exposure to milk or milk-containing foods. It may also be used to evaluate a suspected food allergy.

How is the test performed?

A blood sample is collected and analyzed in a laboratory to detect alpha-lactalbumin-specific IgE. The result is usually reported as an antibody concentration with an accompanying laboratory interpretation.

How do I prepare for the test?

No special preparation is usually required. Tell your clinician about any medicines you take, especially antihistamines, because they can sometimes affect allergy-test results. Do not stop prescribed medication unless your clinician advises you to do so.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Alpha-Lactalbumin IgE

Frequently asked questions

Does a positive result mean I am allergic to milk?
Not necessarily. It shows sensitization to alpha-lactalbumin, and your clinician must interpret it alongside your symptoms and medical history to determine whether you have a clinically relevant allergy.
What if I avoid milk and my symptoms improve?
Improvement after avoiding milk can support the suspicion of a milk-related reaction, but it does not identify the specific protein or cause. Discuss the result with your clinician.
Can antihistamines affect this test?
They may reduce detectable IgE and lead to a falsely lower result. Inform your clinician about all medicines and supplements before testing, and follow their instructions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy