Cerebrospinal Fluid Protein Electrophoresis (Qualitative)
This test measures the protein composition in your cerebrospinal fluid (CSF) to help identify abnormalities in protein distribution, which can indicate conditions like multiple sclerosis, infections, or tumors.
["Assessing protein patterns in CSF can reveal underlying neurological issues."]
Key facts at a glance
- LOINC
- 98485-6
- Short code
- AL beta42/ABeta 40 CSF
- Synonyms
- AL beta42/ABeta 40 CSF
- Category
- coagulation
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you have symptoms like headaches, vision changes, numbness, or weakness that might suggest a neurological condition. It’s also used to monitor certain diseases or conditions affecting the central nervous system, such as multiple sclerosis or meningitis.
Sample Collection and Preparation
A small amount of CSF is collected through a procedure called a lumbar puncture (spinal tap). The fluid is then analyzed in the lab to separate proteins based on size and charge, typically using electrophoresis.
What to Expect During the Procedure
The lumbar puncture involves inserting a needle into your lower back to collect CSF. You may feel pressure or a slight sting, but it’s usually brief. You’ll lie on your side with your knees bent, and you may be given a mild sedative to help relax.
Interpreting Results
The results show different protein bands, which can help identify abnormal patterns. For example, high levels of certain proteins might suggest inflammation, demyelination, or other pathologies. Your provider will interpret these findings in the context of your symptoms and medical history.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CSF Protein Electrophoresis (Qual)
Frequently asked questions
This test is critical for diagnosing and managing conditions affecting the brain and spinal cord. For instance, elevated immunoglobulin G (IgG) in the CSF can indicate a demyelinating disease like multiple sclerosis, while abnormal protein bands may suggest infections or tumors.
An abnormal result may indicate an underlying neurological condition, such as multiple sclerosis, meningitis, or a brain tumor. Your healthcare provider will discuss these findings with you and may recommend further testing or treatment based on the results.
Results from this test are typically available within a few days to a week, depending on lab processing times. Your provider will contact you once the results are ready.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy