Alpha-1 Antitrypsin (Serum) Mass Concentration
This test measures the amount of Alpha-1 Antitrypsin, a protein produced by the liver that helps protect the lungs from damage caused by enzymes released during inflammation.
["Alpha-1 Antitrypsin levels help assess lung and liver health, particularly in conditions like emphysema or chronic liver disease."]
Key facts at a glance
- LOINC
- 33203-1
- Short code
- AL beta42 CSF-mCnc
- Synonyms
- AL beta42 CSF-mCnc
- Category
- coagulation
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like persistent coughing, shortness of breath, or liver-related issues, especially if you have a family history of Alpha-1 Antitrypsin deficiency. It may also be used to monitor lung or liver function in certain chronic conditions.
What to Expect Before the Test
No special preparation is typically needed. You may have a small needle inserted into your arm to draw blood. If you’re nervous, let your healthcare provider know so they can help make the process more comfortable.
What the Results Mean
Lower than expected levels might indicate Alpha-1 Antitrypsin deficiency, which can lead to lung diseases or liver problems. Higher levels may be seen in certain liver diseases or during pregnancy. Your results will be discussed with you by your healthcare provider.
Common Conditions Monitored
This test is often used to diagnose or monitor Alpha-1 Antitrypsin deficiency, chronic obstructive pulmonary disease (COPD), or liver diseases like cirrhosis.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Alpha-1 Antitrypsin deficiency can cause progressive lung damage (like emphysema) and liver disease. Early detection through blood tests can help manage symptoms and prevent complications, such as lung infections or liver failure.
Short name
Alpha-1 Antitrypsin (Serum)
Frequently asked questions
What causes abnormal Alpha-1 Antitrypsin levels?
How often should I get this test?
Can diet or lifestyle changes affect Alpha-1 Antitrypsin levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy