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Albumincsfql

Published: July 31, 2026Updated: August 17, 2026

A test that checks for the presence of albumin protein in the fluid surrounding the brain and spinal cord.

Quick summary

{"Albumin is normally found in blood but should not be present in cerebrospinal fluid (CSF)","The presence of albumin in CSF may indicate damage to the blood-brain barrier","This test helps doctors diagnose conditions affecting the central nervous system","Abnormal results may suggest infection, inflammation, or bleeding in the brain or spinal cord","The test is performed on a sample of CSF collected via lumbar puncture (spinal tap)"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
43711-1
Short code
ALB-CSF
Synonyms
Albumin CSF Ql
Category
chemistry
Sample
csf
Container
Sterile CSF collection tube (plain red top or sterile container)
Units
not specified
Ref low
10
Ref high
30
Critical range
1.5 not specified – 100 not specified
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Immunonephelometry, Turbidimetry, or Immunofixation Electrophoresis
CPT
82040
SNOMED
314198006
Specimen volume
1-2 mL CSF minimum
Stability
Analyze within 2 hours of collection. If delay >2 hours, store at 2-8°C for up to 24 hours. Frozen storage (-20°C) for longer periods may affect results.
Hemolysis max
200
TAT
24–72 hours
Order
routine

What is this test?

The CSF Albumin test detects whether albumin, a protein normally found in blood, is present in cerebrospinal fluid. Cerebrospinal fluid is a clear, colorless fluid that surrounds and protects the brain and spinal cord. A healthy blood-brain barrier prevents albumin from passing from the blood into the CSF. When this barrier is damaged or compromised, albumin can leak into the CSF, which this test can detect.

Reference range

Presentnot specified

Specimen: csf

No special preparation required; CSF obtained via lumbar puncture

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How is the CSF sample collected?
The sample is collected through a procedure called a lumbar puncture, also known as a spinal tap. A healthcare provider inserts a thin needle into the lower back to withdraw cerebrospinal fluid from the space around the spinal cord. The procedure is usually performed while you lie on your side or sit leaning forward.
Does the test require any special preparation?
You may need to stop taking certain medications, such as blood thinners, before the procedure. Your doctor will provide specific instructions. The procedure itself takes about 15-30 minutes, and you may be asked to lie flat for a short time afterward to reduce the risk of headache.
What do abnormal results mean?
The presence of albumin in CSF is not normal and typically indicates an underlying problem. Higher levels may suggest more severe damage to the blood-brain barrier. However, your doctor will interpret the results in context with your symptoms, medical history, and other test results to make an accurate diagnosis.
Is the test painful?
You may feel some discomfort or pressure during the lumbar puncture, but the area is numbed with a local anesthetic. Some people experience a headache afterward, which can usually be managed with rest and plenty of fluids.
  1. 1
    MedlinePlus - Lumbar PunctureSource
  2. 2
    Mayo Clinic - MeningitisSource
  3. 3
    National Multiple Sclerosis SocietySource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy