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Serum Albumin Test

Published: July 31, 2026Updated: August 10, 2026

A blood test that measures the amount of albumin, an important protein made by your liver, to help your doctor assess your overall health.

Quick summary

{"Albumin is a protein made by the liver that helps transport nutrients and maintain fluid balance","This test helps doctors assess liver function, kidney health, and nutritional status","Low albumin levels may indicate liver disease, kidney problems, or malnutrition","The test is performed on a blood sample drawn from a vein in your arm"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
109884-7
Short code
ALB
Synonyms
Albumin Msmt Fld
Category
chemistry
Sample
serum
Container
Serum separator tube (SST/gold top) or plain red top tube
Units
not specified
Ref low
3.5
Ref high
5.5
Critical range
2 not specified – 6 not specified
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Bromocresol green (BCG) colorimetric assay
CPT
82040
SNOMED
271295004
Specimen volume
2-5 mL of venous blood
Stability
Room temperature: 7 days; Refrigerated (2-8°C): 14 days; Frozen (-20°C): 30 days
Hemolysis max
50
Lipemia max
300
Icterus max
20
TAT
1–4 hours
Order
routine

What is this test?

The serum albumin test measures the amount of albumin in your blood. Albumin is a crucial protein produced by your liver that plays several important roles in your body: it helps transport hormones, vitamins, and other substances; maintains proper fluid balance between blood vessels and tissues; and provides your body with necessary proteins for growth and tissue repair.

Why might I need this test?

Your doctor may order a serum albumin test as part of a comprehensive metabolic panel or liver function tests. It is commonly used to: evaluate how well your liver is functioning, check your nutritional status (especially if you have conditions like malnutrition or after surgery), monitor kidney disease or syndrome, and help diagnose certain chronic illnesses. The test is often performed during routine health checkups or when symptoms suggest liver or kidney problems.

How is the test performed?

A healthcare professional will draw a small sample of blood from a vein in your arm using a needle. The blood sample is then sent to a laboratory for analysis. You do not need to fast before this test, though your doctor may instruct you otherwise based on your specific situation. The procedure only takes a few minutes and is generally well-tolerated with minimal discomfort.

Understanding your results

Normal albumin levels typically range from 3.5 to 5.0 g/dL (35-50 g/L), though reference ranges may vary slightly between laboratories. Low albumin levels (hypoalbuminemia) can indicate liver disease, kidney disease (especially nephrotic syndrome), malnutrition, inflammation, or certain digestive disorders. High albumin levels (hyperalbuminemia) are less common and may indicate dehydration. Your doctor will interpret your results in context with other tests and your overall health condition.

Reference range

No established adult reference range (varies by fluid type; interpret with serum albumin and clinical context)not specified

Specimen: serum

None; body fluid specimen collected by appropriate invasive procedure

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Serum albumin is a critical marker for assessing liver function since the liver is the sole organ responsible for producing this protein. Decreased albumin levels may signal chronic liver disease such as cirrhosis or hepatitis. In kidney disease, albumin may leak into urine (proteinuria), reducing blood albumin levels. This test also serves as an important nutritional marker, as albumin levels drop during prolonged malnutrition or severe illness. Additionally, albumin measurement helps doctors monitor disease progression and treatment effectiveness, particularly in conditions affecting the liver, kidneys, or digestive system.

Frequently asked questions

Do I need to fast before the albumin test?
Typically, no fasting is required for a serum albumin test. However, since this test is often part of a larger metabolic panel, your doctor may ask you to fast for 8-12 hours if other tests like glucose or lipid panels are included. Always follow your healthcare provider's specific instructions.
What can cause low albumin levels besides liver disease?
Several conditions can cause low albumin levels, including kidney disease (where albumin is lost in urine), malnutrition or poor dietary intake, chronic inflammatory conditions, certain digestive disorders that impair protein absorption (such as Crohn's disease or celiac disease), heart failure, and severe burns or wounds that cause protein loss. Some medications can also affect albumin levels.
How often should albumin levels be checked?
The frequency of testing depends on your individual health situation. For routine health monitoring, albumin may be checked annually as part of a comprehensive metabolic panel. If you have a known liver or kidney condition, your doctor may order this test more frequently—monthly, quarterly, or as needed—to monitor your condition and treatment response. Follow your healthcare provider's recommendations for testing frequency.
Can lifestyle changes improve albumin levels?
Yes, certain lifestyle changes can help improve albumin levels if they are low due to nutritional causes. These include eating a balanced diet rich in protein (from sources like lean meats, fish, eggs, legumes, and dairy), reducing alcohol consumption, maintaining proper hydration, and managing underlying health conditions. However, if low albumin is due to liver or kidney disease, medical treatment of the underlying condition is necessary. Always consult your doctor before making significant dietary changes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy