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Albuminpcarmcnc

Published: July 31, 2026Updated: August 10, 2026

This test measures the amount of albumin protein in the fluid surrounding the heart (pericardial fluid).

Quick summary

{"Albumin is a protein that helps maintain fluid balance in the body","This test helps doctors determine the cause of fluid buildup around the heart","Results can distinguish between different types of pericardial fluid accumulation","The test is performed on fluid collected from pericardiocentesis","Abnormal levels may indicate infection, inflammation, or other heart conditions"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
51693-0
Short code
ALB PF
Synonyms
Albumin Pcar-mCnc
Category
chemistry
Sample
serum
Container
Sterile collection tube (red top or SST) or sterile container without additives for fluid analysis
Units
not specified
Ref low
1.5
Ref high
3.5
Critical range
1 not specified – —
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Colorimetric assay (bromocresol green or bromocresol purple method)
CPT
82040
SNOMED
275275008
Specimen volume
1-3 mL of pericardial fluid minimum; 5-10 mL preferred for comprehensive analysis
Stability
Refrigerated (2-8°C) for up to 72 hours; freeze at -20°C for longer storage. Avoid repeated freeze-thaw cycles.
Hemolysis max
50
Lipemia max
100
Icterus max
20
TAT
1–24 hours
Order
routine

What is this test?

The Pericardial Fluid Albumin test measures the concentration of albumin, a protein produced by the liver, in the fluid found between the layers of the membrane surrounding the heart (pericardium). This fluid is called pericardial fluid.

How is the sample collected?

Pericardial fluid is collected through a procedure called pericardiocentesis, where a thin needle is inserted into the pericardial sac to withdraw fluid. This is typically done under ultrasound guidance by a trained cardiologist or radiologist.

Why is albumin measured in pericardial fluid?

Albumin levels in pericardial fluid help doctors understand the nature of fluid accumulation around the heart. By comparing albumin levels in the pericardial fluid to blood albumin levels, physicians can determine whether the fluid is a transudate (caused by systemic conditions like heart failure or kidney disease) or an exudate (caused by local inflammation, infection, or malignancy).

Reference range

No established reference rangenot specified

Specimen: serum

No fasting or special preparation; specimen obtained by pericardiocentesis or intraoperatively

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is this test painful?
The pericardiocentesis procedure to collect the fluid is performed under local anesthesia, so you should not feel pain during the procedure. You may experience some discomfort at the insertion site afterward.
How long does it take to get results?
Results are typically available within 1-2 days, as the analysis is performed in a clinical laboratory.
What do high albumin levels mean?
High albumin levels in pericardial fluid (exudate) typically indicate inflammation, infection, or malignancy. Further testing is usually needed to identify the specific cause.
What do low albumin levels mean?
Low albumin levels in pericardial fluid (transudate) usually suggest that the fluid buildup is due to systemic conditions like heart failure, kidney disease, or liver cirrhosis, rather than local inflammation or infection.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy