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Serum Albumin Test

Published: July 31, 2026Updated: August 10, 2026

A blood test that measures the level of albumin, a protein made by the liver, to evaluate liver function and nutritional status.

Quick summary

{"Albumin is a protein produced by the liver that helps maintain fluid balance in the blood","Low albumin levels may indicate liver disease, kidney problems, or malnutrition","This test is commonly performed as part of routine health checkups and liver function panels"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
103577-3
Short code
ALB
Synonyms
Albumin Ser IA-mCnc
Category
chemistry
Sample
serum
Container
SST (Serum Separator Tube) or plain red top tube
Units
not specified
Ref low
3.5
Ref high
5
Critical range
1.5 not specified – —
Fasting
false
Population
adult
Sex
all
Age range
18–100 years
Method
Immunoassay
CPT
82040
SNOMED
274812006
Specimen volume
1.0-2.0 mL serum minimum
Stability
Room temperature: 7 days; Refrigerated (2-8°C): 14 days; Frozen (-20°C or below): 3 months
Hemolysis max
50
Lipemia max
300
Icterus max
20
TAT
4–24 hours
Order
routine

What is this test?

The Serum Albumin test measures the amount of albumin, a important protein, in your blood. Albumin is produced by the liver and plays several vital roles in maintaining your health. It helps keep fluid inside your blood vessels, carries hormones, vitamins, and other substances throughout your body, and helps with tissue repair.

Why is this test performed?

Your doctor may order this test to check how well your liver is functioning, assess your nutritional status, or help diagnose certain medical conditions. It is often part of a comprehensive metabolic panel or liver function test. The test can help identify liver disease, kidney disorders, or problems with protein absorption.

How is the test done?

A healthcare professional will draw a small blood sample from a vein in your arm. The procedure only takes a few minutes and is generally not painful. You may experience slight discomfort or a bruise at the puncture site, but this typically resolves quickly. Fasting is usually not required for this test, but follow your doctor's specific instructions.

Reference range

3.5-5.0 g/dLnot specified

Specimen: serum

No fasting or special preparation required

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Do I need to fast before this test?
Fasting is typically not required for a serum albumin test. However, always follow your healthcare provider's specific instructions, as other tests in the same blood draw may require fasting.
What do low albumin levels mean?
Low albumin can result from liver disease (where the liver cannot produce enough albumin), kidney disease (where albumin is lost through urine), malnutrition or poor diet, digestive disorders that affect nutrient absorption, or chronic illnesses that cause inflammation. Your doctor will interpret your results in the context of your overall health.
What do high albumin levels mean?
High albumin is less common and often indicates dehydration. It may also occur in cases of severe vomiting or diarrhea. In rare cases, it can be related to certain genetic conditions. Your healthcare provider will determine if this requires further investigation.
Is the test safe?
Yes, this is a standard blood test with minimal risks. Possible side effects include slight pain or bruising at the injection site, lightheadedness, and in rare cases, infection. These risks are generally minor and temporary.
  1. 1
    MedlinePlus - Albumin Blood TestSource
  2. 2
    Mayo Clinic - Low AlbuminSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy