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Serum Albumin Blood Test

Published: July 31, 2026Updated: August 10, 2026

The serum albumin test is a simple blood test that measures the level of albumin, a key protein produced by your liver, to help evaluate how well your liver and kidneys are working and to detect conditions such as liver disease, kidney disease, and malnutrition.

Quick summary

{"Albumin is the main protein in blood, made by the liver","This test helps diagnose liver disease, kidney disease, and nutritional status","Low albumin may indicate liver damage, kidney problems, or malnutrition","The test requires a simple blood draw","Results are typically ready within a day"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
54347-0
Short code
ALB
Synonyms
Albumin SerPl-sCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST/gel tube) or plain red top tube
Units
not specified
Ref low
0.53
Ref high
0.75
Critical range
0.23 not specified – 60 not specified
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Bromocresol green (BCG) or Bromocresol purple (BCP) colorimetric method using spectrophotometry
CPT
82040
SNOMED
271254001
Specimen volume
1-2 mL serum minimum
Stability
Room temperature: 7 days; Refrigerated (2-8°C): 14 days; Frozen (-20°C or below): 3 months
Hemolysis max
50
Lipemia max
300
Icterus max
20
TAT
2–24 hours
Order
routine

What is this test?

The serum albumin test measures the amount of albumin in your blood. Albumin is a protein produced by the liver that makes up about 60% of the total protein in your blood. It plays several important roles in maintaining your health, including transporting hormones, vitamins, and medications throughout your body, maintaining fluid balance by keeping fluid inside your blood vessels, and helping with tissue repair and growth.

Why is this test performed?

Your healthcare provider may order an albumin test as part of a routine metabolic panel or comprehensive metabolic panel. It helps evaluate how well your liver is functioning since albumin is produced by the liver. The test also helps assess kidney function, as damaged kidneys may allow albumin to leak into urine. Additionally, it can help diagnose and monitor conditions such as liver disease, kidney disease, malnutrition, and certain inflammatory conditions.

How is the test performed?

A healthcare professional will draw a small blood sample from a vein in your arm using a needle. The sample is then sent to a laboratory for analysis. You do not need to fast before this test, though your doctor may instruct you to do so based on other tests being performed simultaneously.

Understanding your results

Normal albumin levels typically range from 3.5 to 5.0 g/dL (35-50 g/L). However, reference ranges may vary slightly between laboratories. Your doctor will interpret your results based on your overall health and other test findings.

Reference range

0.53-0.75 mmol/Lnot specified

Specimen: serum

No special preparation or fasting required

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low albumin levels (hypoalbuminemia) may indicate liver disease such as cirrhosis or hepatitis, kidney disease such as nephrotic syndrome, malnutrition or malabsorption, chronic inflammatory conditions, heart failure, or certain digestive disorders. High albumin levels (hyperalbuminemia) are less common and usually indicate dehydration. The albumin test is often interpreted together with other liver function tests to get a complete picture of liver health.

Frequently asked questions

Do I need to fast before the albumin test?
Typically, no fasting is required for an albumin test. However, if your blood sample is being used for multiple tests, your doctor may ask you to fast. Always follow your healthcare provider's specific instructions.
What can cause low albumin levels?
Low albumin can be caused by liver disease (since the liver cannot produce enough albumin), kidney disease (where albumin leaks into urine), malnutrition or poor protein intake, chronic inflammation or infection, certain digestive disorders that affect nutrient absorption, and conditions like cirrhosis or hepatitis.
Is the albumin test dangerous?
The risks are minimal and similar to any blood draw. You may experience slight bruising, bleeding, or dizziness at the injection site. These symptoms usually resolve quickly.
How often should albumin be tested?
The frequency depends on your health condition. For routine check-ups, it may be part of annual blood work. If you have liver or kidney disease, your doctor may order this test more frequently to monitor your condition. Follow your healthcare provider's recommendations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy