Plasma Aldosterone Concentration (with Saline Challenge)

Why This Test Is Done

Your doctor may order this test if you have symptoms like high blood pressure, frequent urination, or signs of low potassium. It’s also used to check for conditions like primary aldosteronism (a hormone disorder) or adrenal gland problems that affect salt and water balance.

What to Expect Before the Test

You’ll drink a saline solution (saltwater) before the blood draw. The test involves collecting blood samples at different times to measure aldosterone levels, which helps track how your body responds to the salt challenge.

What the Test Results Mean

Results are compared to your baseline aldosterone levels and how they change after drinking saline. Abnormal results may indicate whether your kidneys are overproducing aldosterone or if another condition is affecting your blood pressure and fluid balance.

Common Conditions Linked to This Test

This test is often used to diagnose conditions like **primary aldosteronism** (a common cause of high blood pressure), **adrenal insufficiency**, or **Cushing’s syndrome** (excess cortisol). It can also help rule out other causes of unexplained high blood pressure or electrolyte imbalances.