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Alpha-1 Globulin, 24-Hour Urine — Electrophoresis, Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures alpha-1 globulin protein excreted over 24 hours using urine protein electrophoresis to help evaluate urinary protein loss.

Quick summary

["This test measures alpha-1 globulin released into the urine and is interpreted with the rest of your kidney and protein tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35708-7
Short code
Alpha1 Glob 24h Ur Elph-mCnc
Synonyms
Alpha1 Glob 24h Ur Elph-mCnc
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
44
Ref high
147
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
84075
SNOMED
27550007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of alpha-1 globulin, a group of proteins, passed into your urine over 24 hours. It is part of urine protein electrophoresis and provides information about protein loss through the kidneys.

Why might I need this test?

It may be ordered when protein is found in your urine or when kidney function needs further evaluation. The result is usually considered with urine albumin, total protein, creatinine, and other parts of the protein-electrophoresis pattern.

How is the test performed?

You collect all urine produced for a full 24-hour period according to your laboratory's instructions. The laboratory measures the collected volume, separates urine proteins by electrophoresis, and determines the amount in the alpha-1 globulin fraction.

How do I prepare for the test?

Follow the laboratory's 24-hour urine-collection instructions exactly, including the start and end times and how the container is stored. Do not change your diet or medication routine unless your clinician specifically tells you to.

Reference range

Adult: 44-147 U/LN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Urine Alpha-1 Globulin

Frequently asked questions

Is this the same as a urine protein test?
It is part of urine protein electrophoresis, which measures different groups of urinary proteins. The alpha-1 globulin result is best interpreted along with albumin, total urine protein, creatinine, and the other electrophoresis fractions.
How is a 24-hour urine sample collected?
Usually, you empty your bladder at the assigned start time and discard that urine, then collect every subsequent urine sample for 24 hours. Follow your laboratory's instructions for the final collection, container handling, and delivery.
Does an abnormal result mean I have kidney disease?
No. An abnormal result may suggest increased protein loss, but it can also be affected by collection completeness and temporary changes in health. Your clinician should interpret it with your other laboratory results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy