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Alpha-1 Globulin, 24-Hour Urine — Electrophoresis, Qualitative

Published: August 9, 2026Updated: August 16, 2026

This test measures the alpha-1 globulin protein fraction in urine collected over 24 hours and separates protein fractions by electrophoresis.

Quick summary

["The result helps evaluate unusual urinary protein excretion, but it is interpreted along with the rest of the urine protein profile."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29945-3
Short code
Alpha1 Glob 24h Ur Ql Elph
Synonyms
Alpha1 Glob 24h Ur Ql Elph
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
44
Ref high
147
Critical range
7.2 N/A – 7.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
84075
SNOMED
27550007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test examines urine for alpha-1 globulin, one of the protein fractions that can be identified by electrophoresis. It is performed on a urine sample collected over 24 hours.

Why might I need this test?

It may be ordered as part of a urine protein evaluation, especially when protein in the urine needs to be characterized. The result can help a clinician investigate kidney conditions or other causes of increased urinary protein.

How is the test performed?

The 24-hour urine sample is processed by electrophoresis to identify and assess the alpha-1 globulin fraction. The laboratory report may describe this fraction as present, increased, or otherwise abnormal.

How do I prepare for the test?

Follow the collection instructions provided by the laboratory, usually including discarding urine at the start of the period and collecting all urine for the next 24 hours. Keep the container refrigerated if instructed, record the total volume, and return the sample promptly. Fasting is generally not required.

Reference range

Adult: 44-147 U/LN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-hour urine alpha-1 globulin electrophoresis

Frequently asked questions

Does this test diagnose a specific kidney disease?
No. It characterizes part of the urine protein pattern and must be interpreted with the rest of your laboratory results and clinical findings.
Why is a 24-hour urine sample needed?
Collecting urine for 24 hours provides a more representative measure of daily urinary protein excretion than a single urine sample.
What if the urine collection is incomplete or the total volume is not recorded?
The result may be difficult or impossible to interpret accurately. Contact the laboratory or ordering clinician for instructions on repeating the collection.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy