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Alpha-1 Globulin, Urine — Electrophoresis, Mass Fraction

Published: August 9, 2026Updated: August 16, 2026

Measures the alpha-1 globulin fraction among proteins in urine, usually as part of urine protein electrophoresis.

Quick summary

["This test helps evaluate unusual urinary protein patterns that may be associated with kidney or other medical conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72593-7
Short code
Alpha1 Glob MFr.DF Ur Elph
Synonyms
Alpha1 Glob MFr.DF Ur Elph
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
44
Ref high
147
Critical range
7.2 N/A – 7.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
84075
SNOMED
27550007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

Urine protein electrophoresis separates urinary proteins into groups based on their size and electrical properties. This test reports the mass fraction of alpha-1 globulin, a group of proteins that includes several different molecules.

Why might I need this test?

This test may be ordered when protein is found in the urine or when the pattern of urinary proteins needs further evaluation. It can help identify an abnormal protein pattern that may require additional testing.

How is the test performed?

A urine sample is analyzed using electrophoresis to separate the proteins present. The laboratory then measures the proportion of protein in the alpha-1 globulin region.

How do I prepare for the test?

Follow the laboratory's urine collection instructions. Some tests use a single urine sample, while others require a timed collection, such as a 24-hour collection; fasting is generally not required unless your clinician gives specific instructions.

Reference range

Adult: 44-147 U/LN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An increased alpha-1 globulin fraction may occur with kidney disease, inflammation, or other conditions that cause abnormal proteins to appear in urine. Results must be interpreted with the urine protein concentration, other electrophoresis findings, kidney function tests, and your symptoms because a low-protein urine sample can affect the reported fractions. An abnormal result does not by itself establish a diagnosis.

Short name

Urine alpha-1 globulin electrophoresis

Frequently asked questions

Is this the same as a serum protein electrophoresis test?
No. Serum protein electrophoresis measures proteins in blood, while this test evaluates their relative distribution in urine.
Does an abnormal result mean I have a specific disease?
No. Abnormal urine protein patterns can have several causes, so your clinician will interpret this result alongside other laboratory findings and clinical information.
Is this an alpha-1 antitrypsin test?
No. Alpha-1 antitrypsin is one protein that can migrate in the alpha region, but this urine electrophoresis measurement is not a specific alpha-1 antitrypsin test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy