Alpha-1 Globulin, Serum/Plasma — Electrophoresis, Mass Concentration
Measures the alpha-1 globulin fraction of blood proteins using electrophoresis. It may help evaluate protein patterns associated with inflammation or liver disease.
["This test measures the alpha-1 globulin fraction of blood proteins as part of protein electrophoresis."]
Key facts at a glance
- LOINC
- 9734-5
- Short code
- Alpha1 Glob Ur Elph-mCnc
- Synonyms
- Alpha1 Glob Ur Elph-mCnc
- Category
- liver
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Ref low
- 44
- Ref high
- 147
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- CPT
- 84075
- SNOMED
- 27550007
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What is this test?
Alpha-1 globulin is a group of blood proteins. This test estimates the amount of this protein fraction using laboratory protein electrophoresis.
Why might I need this test?
It may be ordered as part of a broader evaluation of your blood protein levels, such as when a clinician is investigating inflammation, liver disease, nutritional problems, or an unusual protein pattern.
How is the test performed?
A blood sample is separated by electrophoresis so that the major protein fractions can be measured. The laboratory then calculates or estimates the alpha-1 globulin fraction.
How do I prepare for the test?
This test usually does not require fasting, but follow your clinician's or laboratory's instructions. Tell the laboratory if you are pregnant, have received a blood transfusion, or are taking biotin, because these can sometimes affect testing.
Reference range
Adult: 44-147 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
An increased alpha-1 globulin fraction may occur during acute inflammation or infection and can also be associated with some liver conditions. A decreased fraction may occur with impaired liver protein production, nutritional problems, or certain inherited protein disorders. Results should be interpreted with the other electrophoresis fractions, your medical history, and other laboratory tests.
Short name
Alpha-1 globulin by electrophoresis
Frequently asked questions
Is alpha-1 globulin the same as alpha-1 antitrypsin?
Do I need to fast before this test?
Can a single abnormal result diagnose a disease?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy