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Alpha-2-Globulin, 24-Hour Urine — Electrophoresis, Mass Fraction

Published: August 9, 2026Updated: August 16, 2026

Measures the alpha-2-globulin fraction in protein collected from urine over 24 hours using electrophoresis to help evaluate urinary protein patterns.

Quick summary

["This test evaluates how much alpha-2-globulin is being lost in the urine over a full day."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72588-7
Short code
Alpha2 Glob 24h MFr.DF Ur Elph
Synonyms
Alpha2 Glob 24h MFr.DF Ur Elph
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
44
Ref high
147
Critical range
7.2 N/A – 7.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
84075
SNOMED
27550007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures alpha-2-globulin, a protein, in urine collected for 24 hours. Electrophoresis separates urinary proteins into fractions so the relative amount of alpha-2-globulin can be assessed.

Why might I need this test?

It may be ordered as part of a 24-hour urine protein evaluation when there is concern about kidney disease, increased urinary protein loss, or an unusual urine protein pattern. It is usually interpreted with other urine and blood test results.

How is the test performed?

You collect all urine for exactly 24 hours using the container and instructions provided by the laboratory. The laboratory then measures the amount of protein and uses electrophoresis to determine the alpha-2-globulin fraction.

How do I prepare for the test?

No fasting is usually required. Follow the laboratory's 24-hour collection instructions carefully, and tell your clinician if you have fever, illness, vigorous exercise, menstruation, or major changes in medication before or during collection.

Reference range

Adult: 44-147 U/LN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An abnormal alpha-2-globulin fraction may occur with inflammation, changes in blood protein levels, liver conditions, or altered kidney filtering. The finding is not diagnostic by itself and should be interpreted with total urine protein, urine albumin, kidney function tests, and your clinical history.

Short name

24-Hour Urine Alpha-2-Globulin

Frequently asked questions

Is fasting required for this test?
No, fasting is generally not required. The main preparation is collecting all urine accurately for the full 24-hour period according to the laboratory's instructions.
What does an abnormal result mean?
It may reflect inflammation, liver-related changes in blood proteins, or how the kidneys are handling proteins. Your clinician will interpret it alongside other laboratory results because this test alone cannot identify a specific condition.
Can this test be performed on a regular urine sample?
This test specifically requires a 24-hour urine collection when ordered as a 24-hour measurement. Other urine protein tests may use a single specimen, so confirm the collection instructions with the laboratory.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy