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Alpha-2 Globulin, 24-Hour Urine — Electrophoresis, Mass Fraction

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of alpha-2 globulin protein in a 24-hour urine collection using urine protein electrophoresis.

Quick summary

["This test measures alpha-2 globulin released into urine and may help evaluate protein loss or certain inflammatory conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13987-3
Short code
Alpha2 Glob 24h MFr Ur Elph
Synonyms
Alpha2 Glob 24h MFr Ur Elph
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
44
Ref high
147
Critical range
7.2 N/A – 7.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
84075
SNOMED
27550007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

Alpha-2 globulin is a group of proteins found in blood. This test measures the amount in urine, where it can appear when kidney filtering is affected or when certain proteins increase in the blood.

Why might I need this test?

Your clinician may order this test as part of a 24-hour urine protein assessment, particularly if there is swelling, foamy urine, reduced urine output, or other signs of kidney or systemic disease.

How is the test performed?

You collect all urine for 24 hours in a labeled container. The laboratory then separates urine proteins by electrophoresis and measures the alpha-2 globulin fraction.

How do I prepare for the test?

Follow your clinician's collection instructions and record when you begin and finish the 24-hour period. The container and collection time should match those specified by the laboratory.

Reference range

Adult: 44-147 U/LN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An increased urine alpha-2 globulin level may occur with increased blood levels of these proteins, including during some acute inflammatory or infection-related conditions. It may also reflect impaired kidney filtering, so results are usually interpreted alongside the other urine protein fractions and kidney function tests.

Short name

24-Hour Urine Alpha-2 Globulin

Frequently asked questions

Does this test diagnose a specific condition?
No. It is usually one part of a broader evaluation of urine proteins, symptoms, kidney function, and other laboratory findings.
Why is a 24-hour urine collection needed?
A 24-hour collection accounts for urine produced throughout the day and night, giving a more complete measurement than a single urine sample.
Can I collect the urine at home?
Yes, if instructed by your clinician or laboratory. Use the provided container, collect all urine during the specified period, and store or return it as directed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy