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Alpha-2-Globulin, 24-Hour Urine — Electrophoresis, Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures alpha-2 globulin in urine collected over 24 hours using electrophoresis to help evaluate the urinary protein pattern.

Quick summary

["This test measures alpha-2 globulin in a 24-hour urine collection to help assess urinary protein excretion."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38189-7
Short code
Alpha2 Glob 24h Ur Elph-mCnc
Synonyms
Alpha2 Glob 24h Ur Elph-mCnc
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
44
Ref high
147
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
84075
SNOMED
27550007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of alpha-2 globulin, a group of proteins, in urine collected over 24 hours. Urine electrophoresis separates proteins into fractions so that the alpha-2 globulin fraction can be measured.

Why might I need this test?

It may be ordered to evaluate the types of proteins appearing in urine, particularly when kidney disease, abnormal urine protein findings, or suspected protein loss is being investigated. It is usually interpreted with other urine protein measurements and kidney function tests.

How is the test performed?

You collect all urine for a full 24-hour period in the container provided by the laboratory. The collection is then analyzed by electrophoresis, and the amount of alpha-2 globulin is reported as a mass concentration.

How do I prepare for the test?

Follow the laboratory's collection instructions carefully, including the start and end times, storage requirements, and any advice about continuing or withholding medicines. If urine is missed or the collection is shorter than instructed, ask the laboratory whether the collection should be repeated.

Reference range

Adult: 44-147 U/LN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-hour urine alpha-2 globulin

Frequently asked questions

Do I need to fast for this test?
Fasting is generally not required unless the laboratory gives specific instructions. Follow the instructions provided for medicines, fluid intake, and urine collection.
Why is urine collected for 24 hours?
A 24-hour collection measures substances excreted over a complete day more accurately than a single urine sample. This helps account for changes in urine output and protein excretion throughout the day.
Does an abnormal result diagnose kidney disease?
No. An abnormal alpha-2 globulin result can contribute to an assessment but is not diagnostic by itself. Your clinician will consider it alongside symptoms, other urine findings, and kidney function tests.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy