Alpha-2 Globulin, Serum/Plasma — Electrophoresis, Derived Mass Fraction
Measures the relative share of alpha-2 globulins in total serum or plasma protein using electrophoresis to help evaluate the protein pattern.
["This test reports the proportion of total protein found in the alpha-2 globulin region."]
Key facts at a glance
- LOINC
- 72590-3
- Short code
- Alpha2 Glob MFr.DF SerPl Elph
- Synonyms
- Alpha2 Glob MFr.DF SerPl Elph
- Category
- liver
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 44
- Ref high
- 147
- Critical range
- 7.2 N/A – 7.6 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- CPT
- 84075
- SNOMED
- 27550007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test uses protein electrophoresis to measure the fraction of total protein in the alpha-2 globulin region. The result is a relative proportion rather than the amount of one specific protein.
Why might I need this test?
It may be ordered as part of a serum or plasma protein electrophoresis panel. Your clinician may use it with the other protein fractions to investigate an unusual protein pattern or monitor a protein-related condition.
How is the test performed?
A blood sample is separated into its protein components using electrophoresis. The laboratory then estimates the relative amount of protein in the alpha-2 globulin region and compares it with the other fractions.
How do I prepare for the test?
Fasting is usually not required, but follow any instructions from your healthcare provider or laboratory. Tell the laboratory if you are pregnant or recently received a blood transfusion, because these can affect protein electrophoresis results.
Reference range
Adult: 44-147 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
An increased or decreased alpha-2 globulin fraction can occur with several conditions, including inflammation, liver disease, kidney disease, nutritional changes, or the presence of another protein. The result is interpreted with the other electrophoresis fractions and your clinical findings rather than on its own. Your healthcare provider can explain whether a change is meaningful for you.
Short name
Alpha-2 globulin fraction
Frequently asked questions
Does this test measure one specific protein?
Is fasting required for this test?
Why can my alpha-2 globulin result change?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy