Alpha-2 Globulin, Urine — Electrophoresis, Mass Fraction
A urine protein electrophoresis test that measures the alpha-2 globulin fraction. It may help evaluate protein loss and kidney function alongside other urine tests.
["This test measures alpha-2 globulin in urine to help assess urinary protein loss and possible kidney abnormalities."]
Key facts at a glance
- LOINC
- 72589-5
- Short code
- Alpha2 Glob MFr.DF Ur Elph
- Synonyms
- Alpha2 Glob MFr.DF Ur Elph
- Category
- liver
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Ref low
- 44
- Ref high
- 147
- Critical range
- 7.2 N/A – 7.6 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- CPT
- 84075
- SNOMED
- 27550007
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test uses electrophoresis to separate the proteins in a urine sample and measure the alpha-2 globulin fraction. It is often interpreted with urine protein and creatinine measurements.
Why might I need this test?
Your clinician may order this test to investigate unexplained protein in the urine, monitor certain kidney conditions, or evaluate how well your kidneys are filtering protein. It may also be used as part of a broader assessment of urine proteins.
How is the test performed?
A urine sample is collected and analyzed in the laboratory. Electrophoresis separates the urine proteins into groups, allowing the laboratory to determine the relative amount of alpha-2 globulin.
How do I prepare for the test?
No special diet or fasting is usually required. Collect urine using the container and schedule provided by your clinician; if a 24-hour collection is requested, follow all timing and storage instructions carefully.
Reference range
Adult: 44-147 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
An increased alpha-2 globulin fraction may occur when more protein is being lost in the urine, including with some forms of kidney filtering or reabsorption problems. Inflammation and certain other medical conditions can also affect the result. The finding should be interpreted with the full urine protein pattern, creatinine level, symptoms, and other kidney tests because it does not identify a specific condition by itself.
Short name
Urine Alpha-2 Globulin
Frequently asked questions
What does alpha-2 globulin in urine measure?
Does an abnormal result mean I have kidney disease?
Do I need to collect urine for a specific time?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy