Alpha-2 Globulin, Fluid — Electrophoresis, Mass Fraction
Measures the proportion of alpha-2 globulin in a fluid sample using protein electrophoresis.
["This test helps evaluate the distribution of proteins in a body-fluid sample."]
Key facts at a glance
- LOINC
- 17814-5
- Short code
- Alpha2 Glob MFr Fld Elph
- Synonyms
- Alpha2 Glob MFr Fld Elph
- Category
- liver
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 44
- Ref high
- 147
- Critical range
- 7.2 N/A – 7.6 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- CPT
- 84075
- SNOMED
- 27550007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
Alpha-2 globulin is part of the body's protein system. This laboratory test uses electrophoresis to separate proteins in a fluid sample and determine the fraction or proportion made up of alpha-2 globulin.
Why might I need this test?
This test may be ordered as part of a protein profile to evaluate inflammation, liver or kidney function, or an unusual increase in certain proteins. It is also used when a clinician is investigating a possible monoclonal protein disorder.
How is the test performed?
A sample of the specified body fluid is analyzed using electrophoretic separation. The laboratory identifies the alpha-2 globulin region and estimates its proportion relative to the other separated proteins.
How do I prepare for the test?
Preparation depends on the type of fluid being tested. Follow the collection instructions provided by your healthcare professional, and tell the laboratory if you are pregnant or have recently received certain medicines, such as IV immunoglobulin, because these can affect protein results.
Reference range
Adult: 44-147 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
An increased or decreased alpha-2 globulin fraction may occur with inflammation, liver disease, kidney disease, or changes in protein production. An isolated abnormal result is not a diagnosis and should be interpreted with other laboratory findings, symptoms, and the type of fluid tested.
Short name
Alpha-2 globulin fraction
Frequently asked questions
Does this test measure alpha-2 macroglobulin specifically?
What does an abnormal alpha-2 globulin fraction mean?
Which body fluid is used for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy