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Alpha-2 Globulin, Urine — Electrophoresis, Mass Fraction

Published: August 9, 2026Updated: August 16, 2026

A urine protein electrophoresis test that estimates the fraction of urinary protein in the alpha-2 globulin band.

Quick summary

["This test measures the proportion of protein in your urine that is classified as alpha-2 globulin."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13993-1
Short code
Alpha2 Glob MFr Ur Elph
Synonyms
Alpha2 Glob MFr Ur Elph
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
44
Ref high
147
Critical range
7.2 N/A – 7.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
84075
SNOMED
27550007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test uses urine protein electrophoresis to separate urinary proteins into groups. It estimates the mass fraction, or relative proportion, of protein in the alpha-2 globulin group.

Why might I need this test?

It may be ordered as part of an evaluation of protein in the urine, abnormal kidney function, or suspected kidney disease. It is usually interpreted with other urine tests, including total urine protein and creatinine.

How is the test performed?

A urine specimen is analyzed by electrophoresis, which separates proteins according to their electrical properties. The laboratory then estimates how much of the detected protein belongs to the alpha-2 globulin fraction.

How do I prepare for the test?

Fasting is generally not required. Collect the urine using the container and collection schedule provided by your clinician or laboratory; if a timed or 24-hour collection is ordered, include all urine for the specified period.

Reference range

Adult: 44-147 U/LN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An increased or decreased alpha-2 globulin fraction may reflect changes in urinary protein production, filtration, or reabsorption. These changes can occur with several kidney or systemic conditions, so the result should be interpreted with the rest of your urine studies and your clinical history. A single result does not by itself establish a diagnosis.

Short name

Urine Alpha-2 Globulin

Frequently asked questions

What does the alpha-2 globulin fraction measure?
It estimates the proportion of the proteins detected in your urine that falls into the alpha-2 globulin group during electrophoresis.
Does this test diagnose kidney disease?
No. It is one part of a broader evaluation and is usually reviewed alongside total urine protein, creatinine, other protein fractions, and your symptoms.
Do I need to fast for this urine test?
Fasting is usually unnecessary, but you should follow the laboratory's urine collection instructions. Ask your clinician whether a first-morning, timed, or 24-hour specimen is required.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy