Alpha-2 Globulin, Serum — Electrophoresis, Mass Concentration
Measures the alpha-2 globulin fraction of serum proteins using electrophoresis. It is usually interpreted with the complete serum protein electrophoresis.
["This test measures part of the protein in blood and may help evaluate inflammation, liver function, kidney protein loss, or a possible monoclonal protein."]
Key facts at a glance
- LOINC
- 2869-6
- Short code
- Alpha2 Glob Snv Elph-mCnc
- Synonyms
- Alpha2 Glob Snv Elph-mCnc
- Category
- liver
- Sample
- fluid
- Container
- Sterile tube
- Units
- N/A
- Ref low
- 44
- Ref high
- 147
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- CPT
- 84075
- SNOMED
- 27550007
- Specimen volume
- 2-5 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h
- Hemolysis max
- 300
- TAT
- 4–24 hours
- Order
- routine
What is this test?
Alpha-2 globulin is a region of the protein pattern measured in blood serum. Serum protein electrophoresis separates the major protein groups so their relative amounts can be assessed.
Why might I need this test?
This measurement is often part of a broader evaluation of protein levels. It may be used to investigate inflammation, liver disease, kidney conditions that cause protein loss, nutritional problems, or an unusual protein pattern.
How is the test performed?
A blood sample is collected, and the serum is analyzed by electrophoresis. The laboratory measures the amount of protein in the alpha-2 globulin region and may compare it with the other protein fractions.
How do I prepare for the test?
This test usually requires no special preparation. Follow any instructions from your healthcare professional, particularly if it is being ordered with other tests that may require fasting.
Reference range
Adult: 44-147 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
An increased alpha-2 globulin fraction may occur with acute inflammation or some liver disorders, although monoclonal proteins can also affect this region. A decreased fraction may occur when the liver makes less protein, the kidneys lose protein, or nutrition is inadequate. Results are not diagnostic by themselves and should be interpreted with the complete protein electrophoresis and other relevant laboratory findings.
Short name
Alpha-2 globulin
Frequently asked questions
Is alpha-2 globulin a single protein?
Does a high or low result confirm a specific disease?
Is this the same as an immunoglobulin or antibody test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy