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Alpha-2 Globulin, Urine — Electrophoresis, Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures urine alpha-2 globulin using protein electrophoresis to help evaluate protein loss and possible kidney or systemic disease.

Quick summary

["This urine protein test can help identify abnormal protein loss and guide further evaluation when interpreted with other kidney tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
77581-7
Short code
Alpha2 Glob ?Tm Ur Elph-mCnc
Synonyms
Alpha2 Glob ?Tm Ur Elph-mCnc
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
44
Ref high
147
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
84075
SNOMED
27550007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

Alpha-2 globulin is one of the protein groups that can be measured in urine. This test uses electrophoresis to separate urine proteins into groups and estimate the amount of alpha-2 globulin present.

Why might I need this test?

This test may be ordered when there is unexplained protein in the urine or when a clinician is evaluating kidney disease, inflammation, or other conditions that can alter urinary proteins. It is usually interpreted alongside urine protein and kidney-function tests.

How is the test performed?

A urine sample is collected and the proteins in it are separated by electrophoresis. The laboratory then estimates the concentration of the alpha-2 globulin fraction.

How do I prepare for the test?

Follow the laboratory's collection instructions, which may request a first-morning or timed urine sample. Tell the laboratory if you have a urinary infection, fever, or recently exercised vigorously, because these can temporarily affect urine protein results.

Reference range

Adult: 44-147 U/LN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine alpha-2 globulin electrophoresis

Frequently asked questions

Does an abnormal result mean I have a kidney disease?
No. An abnormal alpha-2 globulin result can have several causes and does not diagnose kidney disease by itself. Your clinician will consider it along with your other laboratory results and health history.
Why is urine protein electrophoresis used?
Urine protein electrophoresis separates proteins into groups so the laboratory can measure their relative amounts. This can help identify patterns of protein loss that may point toward a particular condition.
Can exercise or illness affect the result?
Yes. Strenuous exercise, fever, inflammation, and urinary infection can temporarily increase protein in the urine. Inform the laboratory about these factors so the result can be interpreted appropriately.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy