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Alpha-2 Globulin, Serum/Plasma — Electrophoresis, Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the alpha-2 globulin protein fraction in blood using electrophoresis and is interpreted alongside liver, kidney, and inflammation markers.

Quick summary

["This test measures part of the blood's protein profile, but abnormal results usually require interpretation with other laboratory findings."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38190-5
Short code
Alpha2 Glob Ur Elph-mCnc
Synonyms
Alpha2 Glob Ur Elph-mCnc
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
44
Ref high
147
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
84075
SNOMED
27550007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

Alpha-2 globulin is a group of blood proteins that includes substances such as haptoglobin and ceruloplasmin. This test measures the alpha-2 fraction as part of serum protein electrophoresis.

Why might I need this test?

This measurement may be included when a clinician is evaluating inflammation, liver function, kidney-related protein loss, or an abnormality in the blood protein pattern. It is usually interpreted together with the rest of the protein electrophoresis and other laboratory results.

How is the test performed?

A blood sample is separated into its liquid portion, and the serum or plasma proteins are separated by electrophoresis. The laboratory then estimates the amount of protein in the alpha-2 globulin fraction.

How do I prepare for the test?

Fasting is generally not required for this test, but follow any instructions from your healthcare professional. Tell the laboratory if you are pregnant or have recently received certain treatments, such as plasma transfusions, because these can affect protein results.

Reference range

Adult: 44-147 U/LN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Alpha-2 Globulin

Frequently asked questions

Is alpha-2 globulin the same as alpha-1 antitrypsin?
No. Alpha-2 globulin is a group of proteins that migrates in the alpha-2 region during electrophoresis. Alpha-1 antitrypsin is a different protein measured and interpreted separately.
Does an abnormal result diagnose a specific condition?
No. Abnormal alpha-2 globulin levels can occur in several conditions, so your clinician will interpret the result alongside other tests and your symptoms.
Does fasting affect the result?
Fasting is usually unnecessary, although your healthcare professional may provide specific preparation instructions. Recent plasma transfusions or certain medications can influence protein electrophoresis results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy