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Alpha-2-Globulin, Urine — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

A urine test that measures the concentration of alpha-2 globulin, a group of proteins associated with kidney filtering and protein metabolism.

Quick summary

["This test measures alpha-2 globulin in urine and may help evaluate abnormal protein loss or kidney disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6888-2
Short code
Alpha2 Glob Ur-mCnc
Synonyms
Alpha2 Glob Ur-mCnc
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
44
Ref high
147
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84075
SNOMED
27550007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the concentration of alpha-2 globulin in urine. Alpha-2 globulins are a group of proteins that circulate in the blood and are normally retained by the kidneys, so small amounts may be released into urine.

Why might I need this test?

A clinician may order this test as part of an evaluation for protein in the urine, kidney filtering problems, or conditions that affect protein levels. It is usually interpreted along with urine protein, creatinine, and other kidney tests.

How is the test performed?

A urine sample is collected and analyzed in the laboratory to identify and quantify the alpha-2 globulin fraction. The result may be reported as the amount of alpha-2 globulin present in the urine.

How do I prepare for the test?

No special preparation is usually needed, but you should follow the urine collection instructions provided by the laboratory or clinician. Tell the care team if you have a known kidney condition, urinary infection, pregnancy, or recently started new medication.

Reference range

Adult: 44-147 U/LN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine alpha-2 globulin

Frequently asked questions

What does alpha-2 globulin measure?
It measures the concentration of a group of urinary proteins. These proteins are normally present in blood but usually appear in urine only in small amounts.
Does a high result confirm a kidney disease?
No. An elevated result can suggest abnormal urinary protein loss but is not diagnostic by itself and must be considered with other laboratory findings and your symptoms.
Is a 24-hour urine collection required?
It depends on the laboratory's testing instructions. Some results are measured from a single urine sample, while others require collection over a full day.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy