Alpha Globulin, Abnormal — Serum/Plasma Electrophoresis, Mass Fraction
Measures the alpha globulin fraction of blood proteins using electrophoresis. An abnormal result can reflect changes in inflammation, liver or kidney function, or immune proteins.
["This test helps identify and evaluate abnormalities in the alpha globulin portion of your blood proteins."]
Key facts at a glance
- LOINC
- 53540-1
- Short code
- Alpha Glob.abnormal MFr SerPl Elph
- Synonyms
- Alpha Glob.abnormal MFr SerPl Elph
- Category
- liver
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 44
- Ref high
- 147
- Critical range
- 7.2 N/A – 7.6 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- CPT
- 84075
- SNOMED
- 27550007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
Alpha globulin is a group of proteins found in blood. This test measures the amount of the alpha globulin fraction and may be reported as abnormal if it is higher or lower than expected. It is generally part of a serum protein electrophoresis panel.
Why might I need this test?
Your clinician may order this test to investigate an unusual protein pattern, unexplained changes in laboratory results, or symptoms that could suggest inflammation, liver disease, kidney disease, or a plasma-cell disorder.
How is the test performed?
A blood sample is collected, and the liquid portion is separated. The proteins are then separated by electrophoresis, and the alpha globulin fraction is measured or assessed for an abnormal pattern.
How do I prepare for the test?
Fasting is usually not required, but follow your clinician's instructions. Tell the laboratory if you are pregnant or recently received a blood transfusion, because either can affect protein electrophoresis results.
Reference range
Adult: 44-147 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Alpha globulin fraction by electrophoresis
Frequently asked questions
Does an abnormal result mean I have a serious illness?
Is this the same as an alpha-1 antitrypsin test?
Will I need follow-up testing?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy