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Alkaline Phosphatase, Urine — Calculated Result

Published: August 9, 2026Updated: August 16, 2026

This test measures alkaline phosphatase activity in urine and may provide a calculated result based on the laboratory's testing method.

Quick summary

["The result can help evaluate bone or liver-related enzyme activity, but urine collection and laboratory methods strongly affect interpretation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107522-5
Short code
Alpha-PHP Ur Cfm
Synonyms
Alpha-PHP Ur Cfm
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
44
Ref high
147
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
CPT
84075
SNOMED
27550007
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

Alkaline phosphatase is an enzyme found in several body tissues, including bone, liver, and bile ducts. This urine test measures the amount of alkaline phosphatase activity in the urine sample.

Why might I need this test?

A urine alkaline phosphatase test may be ordered as part of an evaluation of bone metabolism, liver or biliary disease, or other conditions affecting enzyme levels. The calculated result may adjust the urine measurement for factors such as concentration or collection details.

How is the test performed?

You provide a urine sample in the container specified by the laboratory. The laboratory measures alkaline phosphatase activity using an enzyme-based method and may calculate a value from the urine concentration or other collection information.

How do I prepare for the test?

Follow the laboratory's urine-collection instructions, including whether a first-morning or timed sample is required. If a timed collection is requested, record the start and end times and bring the full specimen as directed.

Reference range

Adult: 44-147 U/LN/A

Specimen: urine

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Higher-than-expected urinary alkaline phosphatase activity may occur with increased bone turnover or with liver and biliary conditions that increase enzyme release. Lower-than-expected activity is less commonly used for diagnosis. Results should be interpreted with urine concentration, collection method, medications, and other blood test results because isolated urine values may be misleading.

Short name

Urine alkaline phosphatase

Frequently asked questions

Is this the same as a blood alkaline phosphatase test?
No. This test measures alkaline phosphatase activity in urine, while a blood alkaline phosphatase test measures the enzyme in blood. The results use different reference information and are not interchangeable.
Why was a calculated result reported?
A calculated result may account for urine concentration, collection timing, or another laboratory-specified factor. Ask the laboratory what adjustment was made if the report does not explain it.
What can affect an urine alkaline phosphatase result?
Urine concentration, hydration, collection timing, recent physical activity, medications, and conditions affecting bone or liver function can affect the result.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy