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Free Alpha-Subunit, Serum/Plasma — Concentration

Published: August 9, 2026Updated: August 16, 2026

A blood test that measures free pituitary alpha-subunit, often interpreted together with FSH and LH to evaluate hormonal activity.

Quick summary

["This test measures free alpha-subunit in blood and is most useful when interpreted alongside other pituitary or reproductive hormone results."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
100836-6
Short code
Alpha subunit free sp7 p chal SerPl-aCnc
Synonyms
Alpha subunit free sp7 p chal SerPl-aCnc
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
44
Ref high
147
Critical range
— – 100 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84075
SNOMED
27550007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of free alpha-subunit in serum or plasma. Alpha-subunit is a protein component shared by several pituitary hormones, including FSH, LH, and TSH.

Why might I need this test?

It may be ordered when a healthcare professional is evaluating a suspected pituitary condition or an abnormality in reproductive hormone production. It is generally interpreted with FSH, LH, TSH, and other laboratory results rather than as a stand-alone test.

How is the test performed?

A blood sample is collected, and the laboratory measures free alpha-subunit using an immunoassay. The results may be reported as a concentration, with the units specified by the laboratory.

How do I prepare for the test?

No special preparation is usually required. Tell your healthcare professional if you are pregnant, taking hormones, or have had recent pituitary surgery, because these factors can affect the results.

Reference range

Adult: 44-147 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated free alpha-subunit level can occur with some pituitary or hypothalamic disorders, including certain pituitary tumors. Levels may also be influenced by pregnancy, hormonal treatment, and changes in pituitary function, so an abnormal result should be interpreted with symptoms and other hormone tests.

Short name

Free alpha-subunit

Frequently asked questions

Is this the same as a FSH or LH test?
No. FSH and LH are complete hormones, while this test measures the free alpha-subunit portion they share. It is usually reviewed alongside FSH and LH results.
Does an elevated result mean I have a pituitary tumor?
No. An elevated level can have several causes and does not by itself establish a tumor. Your healthcare professional will interpret it with your symptoms, examination, and other hormone tests.
Can hormonal medications affect the result?
Yes. Exogenous hormones and some treatments that affect the pituitary can alter alpha-subunit or related hormone measurements. Inform your clinician about all medications and supplements before testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy