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Alplungserplccnc

Published: July 31, 2026Updated: August 10, 2026

A blood test that measures the level of alkaline phosphatase, an enzyme found in various tissues throughout the body.

Quick summary

{"ALP is mainly produced in the liver and bones","High levels may indicate liver disease, bone disorders, or other conditions","Low levels are less common but can indicate malnutrition or certain genetic disorders","The test is performed on a blood sample drawn from a vein","Results are often interpreted together with other liver function tests"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
12806-6
Short code
ALP
Synonyms
ALP Lung SerPl-cCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST/Gold top) or plain red top tube
Units
not specified
Ref low
44
Ref high
147
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Spectrophotometry using p-nitrophenyl phosphate (PNPP) substrate at 405 nm
CPT
84075
SNOMED
271450004
Specimen volume
1.0-2.0 mL serum minimum
Stability
Room temperature: 2-3 days; Refrigerated (2-8°C): 5-7 days; Frozen (-20°C): several weeks
Hemolysis max
50
Lipemia max
300
Icterus max
20
TAT
1–24 hours
Order
routine

What is this test?

The Alkaline Phosphatase (ALP) test measures the amount of this enzyme in your blood. Alkaline phosphatase is produced by various tissues in the body, including the liver, bones, intestines, and kidneys. The test is commonly used to evaluate liver function and detect bone disorders.

Why is this test performed?

Your healthcare provider may order an ALP test to: check for liver diseases such as hepatitis or cirrhosis; detect bone disorders like Paget's disease, osteomalacia, or bone cancers; monitor the effectiveness of treatment for liver or bone conditions; or investigate the cause of symptoms like jaundice, abdominal pain, or bone pain.

How is the test done?

A healthcare professional will draw a small blood sample from a vein in your arm using a needle. The sample is then sent to a laboratory for analysis. You typically do not need to fast before this test, though your doctor may instruct you to do so depending on other tests being performed.

Understanding your results

Normal ALP levels vary by age, sex, and blood type. High ALP levels may indicate liver disease, bile duct obstruction, bone disorders, or certain medications. Low ALP levels are less common and may be seen in malnutrition, zinc deficiency, or rare genetic disorders. Your doctor will interpret your results in the context of your overall health and other test results.

Reference range

44-147 U/Lnot specified

Specimen: serum

No special preparation or fasting required

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings2

Frequently asked questions

Do I need to fast before the ALP test?
Typically, no fasting is required for an ALP test alone. However, if other tests are ordered together, your doctor may ask you to fast. Always follow your healthcare provider's specific instructions.
What can cause a false high ALP result?
Certain factors can temporarily increase ALP levels, including recent bone fractures, healing wounds, eating fatty meals (if intestinal ALP is elevated), pregnancy, or growth spurts in children. Tell your doctor about any medications or supplements you are taking.
Is the ALP test dangerous?
The risks are minimal and include slight bruising, bleeding, or dizziness at the needle site. These side effects are usually temporary and resolve quickly.
How long does it take to get results?
Results are typically available within a few hours to a couple of days, depending on the laboratory. Your healthcare provider will inform you when and how you will receive your results.
What happens if my ALP is abnormal?
An abnormal ALP result does not necessarily mean you have a serious condition. Your doctor will consider your symptoms, medical history, and other test results to determine if additional testing is needed. Follow-up tests may include repeat blood tests, imaging studies, or specialist consultations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy