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Alpplaccfrserpl

Published: July 31, 2026Updated: August 16, 2026

A blood test that measures the ratio of placental alkaline phosphatase to total alkaline phosphatase, used to assess placental function during pregnancy.

Quick summary

{"This test measures placental alkaline phosphatase (PLAP) levels relative to total ALP","It helps evaluate how well the placenta is functioning during pregnancy","Blood sample is collected from a vein in your arm","Results are reported as a ratio or percentage","Abnormal results may require further testing"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15016-9
Short code
ALP Plac CFr SerPl
Synonyms
ALP Plac CFr SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
not specified
Ref low
0
Ref high
0.05
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84075
SNOMED
27550007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

The placental alkaline phosphatase ratio test measures the amount of placental alkaline phosphatase (PLAP) compared to the total amount of alkaline phosphatase (ALP) in your blood. Alkaline phosphatase is an enzyme found in various tissues including the liver, bones, intestines, and placenta. During pregnancy, the placenta produces a specific type of alkaline phosphatase called placental alkaline phosphatase (PLAP).

Why is this test performed?

This test is primarily used to evaluate placental function during pregnancy. The placenta is essential for providing nutrients and oxygen to your growing baby. By measuring the ratio of placental ALP to total ALP, healthcare providers can get insight into how well the placenta is working and whether there are any concerns with placental function.

How is the test performed?

A healthcare professional will draw a small blood sample from a vein in your arm using a needle. The blood is collected into a tube and sent to a laboratory for analysis. The procedure only takes a few minutes and is generally well-tolerated. You may experience minor bruising or soreness at the puncture site, which typically resolves quickly.

What do the results mean?

Results are typically reported as a ratio (PLAP/total ALP) or as a percentage. Your healthcare provider will interpret these results based on your specific situation, including how far along you are in your pregnancy. Normal values may vary by laboratory, so it is important to discuss your specific results with your healthcare provider.

Reference range

0.00-0.05not specified

Specimen: serum

No special preparation or fasting required

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Do I need to fast before this test?
Fasting is typically not required for this test. However, always follow any specific instructions provided by your healthcare provider or the testing laboratory.
Is this test safe during pregnancy?
Yes, this is a simple blood test that is considered safe during pregnancy. It only requires a small blood sample and carries minimal risks, similar to routine blood draws performed during prenatal care.
What can affect my test results?
Several factors can influence alkaline phosphatase levels, including liver function, bone health, certain medications, and other medical conditions. It is important to inform your healthcare provider about all medications and supplements you are taking.
Will I need additional tests if my results are abnormal?
If your results are abnormal, your healthcare provider may recommend additional tests to get more information. These may include other blood tests, ultrasound examinations, or other prenatal screening tests to better understand your situation.
How long does it take to get results?
Results typically take a few days to a week, depending on the laboratory. Your healthcare provider will contact you with the results or discuss them at your next prenatal appointment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy