Alprazolam-Dependent Platelet IgG, Serum/Plasma — Qualitative
A specialized blood test that looks for IgG antibodies that attach to platelets in the presence of alprazolam.
["A positive result can support alprazolam-related immune thrombocytopenia, especially when low platelets and bleeding are also present."]
Key facts at a glance
- LOINC
- 73537-3
- Short code
- Alpraz ind plt IgG SerPl Ql FC
- Synonyms
- Alpraz ind plt IgG SerPl Ql FC
- Category
- liver
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 44
- Ref high
- 147
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- flow-cytometry
- CPT
- 84075
- SNOMED
- 27550007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test checks a blood sample for alprazolam-dependent platelet IgG antibodies. These antibodies attach to platelets when alprazolam is present and can cause the immune system to destroy or inhibit platelets.
Why might I need this test?
It may be ordered when someone taking alprazolam develops a low platelet count, unusual bruising, nosebleeds, or other signs of immune thrombocytopenia. The result can help determine whether alprazolam may be contributing to the platelet problem.
How is the test performed?
A blood sample is separated into serum or plasma and analyzed using a specialized platelet antibody assay. The laboratory checks whether IgG from the sample binds to platelets in the presence of alprazolam.
How do I prepare for the test?
No special preparation is usually required unless the laboratory gives different instructions. Tell your clinician about all medicines you take, including alprazolam, and when you started or stopped it. Do not stop alprazolam abruptly without medical advice.
Reference range
Adult: 44-147 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A positive result indicates that the blood contains IgG that binds to platelets in the presence of alprazolam. In the right clinical setting, this supports drug-dependent immune thrombocytopenia, which may cause bruising, bleeding, and a low platelet count. The result must be interpreted with medication history, platelet count, symptoms, and other laboratory findings because it does not by itself establish the cause of thrombocytopenia.
Short name
Alprazolam-dependent platelet IgG antibody
Frequently asked questions
What does a positive result mean?
Does this test measure my platelet count?
Should I stop taking alprazolam before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy