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Blood Test: What to Expect and What Your Results Mean

Published: August 9, 2026Updated: August 17, 2026

A blood test that measures the amount of ammonia in your blood to evaluate liver function and detect certain metabolic disorders.

Quick summary

{"Measures ammonia levels in your blood","Helps doctors assess liver function and detect liver disease","Used to investigate causes of confusion, drowsiness, or unusual behavior","Requires fasting and specific preparation before the test","Abnormal results may indicate liver problems or metabolic conditions"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
38589-8
Short code
Ammonia Air-mCnc
Synonyms
Ammonia Air-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
— – 200 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

A blood test is a common laboratory procedure in which a small sample of your blood is collected and analyzed to evaluate your overall health, screen for medical conditions, or monitor a diagnosis you already have. The sample is checked for blood cells, chemicals, proteins, and other markers that show how well your organs and body systems are functioning.

The Blood Ammonia Test measures the level of ammonia in your bloodstream. Ammonia is a waste product that is normally processed by your liver and excreted from your body. When your liver cannot properly remove ammonia, it can build up in your blood and potentially reach your brain, causing serious health problems.

Your doctor may order this test to help diagnose the cause of symptoms such as fatigue, weakness, or unexplained changes in your body, to screen for conditions before they cause problems, to check how well your organs are working, or to track whether a treatment or medication is helping you as expected.

Your doctor may order this test if you have symptoms such as confusion, drowsiness, trembling hands, or difficulty speaking. It is commonly used to: assess liver function, monitor liver disease progression, evaluate for hepatic encephalopathy (a condition where liver disease affects brain function), and detect certain metabolic or genetic disorders.

Preparation is usually simple. Continue taking your regular medications unless your doctor tells you otherwise, and drink plenty of water so your veins are easier to find. If fasting is required, avoid all food and drinks except water for 8 to 12 hours before the test. Wear a shirt with loose sleeves so the draw site on your arm is easy to reach.

Follow these important preparation steps: Fast (do not eat) for 8-12 hours before the test as instructed by your doctor. Avoid smoking before the test, as smoking can increase ammonia levels. Inform your doctor about all medications you are taking, as some medicines can affect test results. Avoid strenuous exercise before the test, as exercise can temporarily increase ammonia levels. Rest quietly before having your blood drawn.

A trained phlebotomist will wrap an elastic band around your upper arm, clean the site with an antiseptic, and insert a thin needle into a vein, usually in your arm. You may feel a quick pinch or a slight sting. The blood is collected into one or more small tubes, the needle is removed, and a bandage is applied. The whole process usually takes less than ten minutes.

A healthcare professional will draw a small blood sample from a vein in your arm using a needle. The sample will be placed in a special tube and sent to a laboratory for analysis. The test itself takes only a few minutes, and you may experience minor discomfort or bruising at the injection site.

Your report will list your values next to a reference range, which represents the levels typically seen in healthy people. A value slightly outside the range does not always mean something is wrong, because factors such as age, diet, hydration, and medications can affect results. Review your results with your doctor, who will explain what they mean for you and whether any follow-up testing or treatment is needed.

Normal ammonia levels typically range from 15 to 45 micromoles per liter (μmol/L), though reference ranges may vary by laboratory. High ammonia levels (hyperammonemia) may indicate liver disease, liver failure, hepatitis, cirrhosis, or certain metabolic disorders. Your doctor will interpret your results based on your overall health, symptoms, and other test results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

What are the symptoms of high ammonia levels?
Symptoms may include confusion, drowsiness, difficulty concentrating, trembling or shaking, slurred speech, mood changes, and in severe cases, coma. These symptoms often worsen after eating protein-rich meals.
What can cause high ammonia levels besides liver disease?
Besides liver disease, high ammonia levels can be caused by certain genetic metabolic disorders, kidney failure, severe infections, gastrointestinal bleeding, dehydration, and some medications. In rare cases, it can result from a high-protein diet or excessive muscle breakdown.
How is high ammonia levels treated?
Treatment depends on the underlying cause. For liver-related high ammonia, treatments may include lactulose (a medication that helps remove ammonia from the body), antibiotics to reduce intestinal bacteria that produce ammonia, dietary protein restriction, and in severe cases, hospitalization. Always follow your doctor's treatment plan.
Is the blood ammonia test dangerous?
The test is generally very safe. Risks are minimal and include slight pain, bruising, or bleeding at the blood draw site. In rare cases, fainting or infection may occur. The benefits of getting accurate diagnostic information far outweigh these small risks.
How long does it take to get results?
Results are typically available within 1-2 days, though some laboratories may take longer. Your doctor's office will contact you with the results or discuss them at your follow-up appointment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy