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Ammoniaplasmscnc

Published: August 9, 2026Updated: August 17, 2026

A blood test that measures ammonia levels in your plasma to evaluate liver function and detect metabolic disorders.

Quick summary

{"The test measures ammonia, a waste product processed by your liver","High levels may indicate liver disease, kidney problems, or certain metabolic conditions","You may need to fast and avoid smoking before the test","Results help doctors diagnose and monitor conditions affecting liver function"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
35254-2
Short code
Ammonia Plas-msCnc
Synonyms
Ammonia Plas-msCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Critical range
— – 200 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

The Blood Ammonia Test measures the amount of ammonia in your plasma (the liquid part of your blood). Ammonia is a natural waste product created when your body breaks down proteins. Normally, your liver converts ammonia into urea, which your kidneys then excrete through urine. This test helps doctors evaluate how well your liver and kidneys are functioning.

Why do I need this test?

Your doctor may order this test if you have symptoms of liver disease, such as jaundice (yellowing of skin or eyes), confusion, drowsiness, or unusual body odor. It is also used to monitor conditions like hepatic encephalopathy (a brain disorder caused by liver disease), cirrhosis, hepatitis, or Reye's syndrome. Additionally, the test can help evaluate inherited metabolic disorders that affect how your body processes ammonia.

How is the test performed?

A healthcare professional will draw a blood sample from a vein in your arm using a small needle. The blood is collected into a special tube containing an anticoagulant to prevent clotting. The sample must be placed on ice immediately and processed quickly, as ammonia levels can change after the blood is drawn. The entire process only takes a few minutes.

How to prepare for the test

Follow these important preparation steps: Fast (do not eat) for 8-12 hours before the test, as instructed by your doctor. Do not smoke for at least 8 hours before the test, as smoking increases ammonia levels. Avoid strenuous exercise before the test. Inform your doctor about all medications you are taking, as certain drugs can affect ammonia levels. Follow any specific instructions provided by your healthcare team.

Understanding your results

Normal ammonia levels vary slightly by laboratory but are typically between 15-45 micromoles per liter (μmol/L). High levels (hyperammonemia) may indicate liver failure, cirrhosis, hepatitis, kidney failure, certain metabolic disorders, or severe infection. Very high levels can be dangerous and require immediate medical treatment. Your doctor will interpret your results based on your overall health, symptoms, and other test findings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is the blood ammonia test painful?
You may feel a brief sting or pinch when the needle is inserted into your arm. This is typically well-tolerated and only lasts a few seconds. Some people may experience minor bruising at the injection site afterward.
How long does it take to get results?
Results are usually available within 1-2 days, though this may vary depending on the laboratory. Your doctor's office will contact you with the results or discuss them at your follow-up appointment.
What happens if my ammonia levels are high?
High ammonia levels require prompt medical attention. Your doctor will determine the cause and recommend appropriate treatment, which may include medication, dietary changes, or hospitalization in severe cases. Do not ignore elevated results, as very high levels can lead to serious complications including confusion, coma, or brain damage.
Can I take my regular medications before the test?
Inform your doctor about all medications you are taking, as some drugs like valproic acid, diuretics, or certain antibiotics can affect ammonia levels. Your doctor will advise you on which medications to take or avoid before the test.
Are there any risks associated with this test?
The risks are minimal and similar to other blood tests. These may include slight bleeding, bruising, infection, or dizziness. These side effects are usually temporary and resolve on their own.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy