Understanding Your Lab Test: What It Is, How It Is Performed, and What Your Results Mean for Your Health
This laboratory test determines whether slow-growing mycobacteria (such as certain types of tuberculosis or non-tuberculous mycobacteria) are sensitive or resistant to the antibiotic combination of amoxicillin and clavulanate.
{"This test checks if antibiotics can effectively treat a mycobacterial infection","Results help doctors choose the right antibiotics for your treatment","The test is performed on a sample of your blood (serum)","Results typically take several days to weeks because mycobacteria grow slowly"}
Key facts at a glance
- LOINC
- 25310-4
- Short code
- Amoxicillin+Clav Islt SlowMyco
- Synonyms
- Amoxicillin+Clav Islt SlowMyco
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- method-for-slow-growing-mycobacteria
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test, what exactly does it measure or look for in my body, and why is it considered a useful tool for evaluating my overall health?
The Amoxicillin/Clavulanate Susceptibility Test is a laboratory test that determines how well the antibiotic combination of amoxicillin and clavulanate works against slow-growing mycobacteria. Mycobacteria are a type of bacteria that cause infections like tuberculosis (TB) and certain other less common infections. These bacteria grow very slowly in laboratory conditions, which is why special testing methods are required.
How is this test performed, what steps are involved in the procedure, and what should I expect when I arrive for my appointment?
A blood sample is collected from you and sent to a laboratory. In the lab, scientists grow the mycobacteria from your sample and then expose them to amoxicillin/clavulanate to see if the bacteria are killed or inhibited. This process helps determine if the antibiotic will be effective in treating your infection. Because mycobacteria grow slowly, this test may take several days to weeks to complete.
Why might I need this test, and in what situations would my healthcare provider recommend it as part of my care or diagnosis?
Your doctor may order this test if you have a confirmed or suspected infection with slow-growing mycobacteria, such as Mycobacterium tuberculosis or non-tuberculous mycobacteria (NTM). The results help your doctor choose the most appropriate antibiotic treatment, as some mycobacteria are naturally resistant to certain antibiotics. This test is particularly important for treating persistent or difficult-to-cure infections.
What do the results of this test mean, how are normal and abnormal values interpreted, and what are the next steps after I receive my results?
The test result will indicate whether the mycobacteria are 'susceptible' (sensitive) or 'resistant' to amoxicillin/clavulanate. If the bacteria are susceptible, the antibiotic combination is likely to be effective in treating your infection. If the bacteria are resistant, your doctor will need to choose different antibiotics. Your doctor will interpret these results in the context of your overall health and infection status.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This susceptibility test is crucial for guiding appropriate antibiotic therapy in mycobacterial infections. Slow-growing mycobacteria, including Mycobacterium tuberculosis and various non-tuberculous mycobacteria, can be resistant to many standard antibiotics. Testing helps identify which antibiotics will be most effective, reducing treatment failure and preventing the development of antibiotic resistance. The amoxicillin/clavulanate combination is particularly useful because clavulanate inhibits beta-lactamase enzymes that some bacteria produce to destroy antibiotics.
Frequently asked questions
Is the test painful?
How long does it take to get results?
Do I need to fast before this test?
What happens after I get my results?
Sources
- 1
- 2
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy