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Understanding Your Lab Test: What It Is, How It Is Performed, and What Your Results Mean for Your Health

Published: August 9, 2026Updated: August 16, 2026

This laboratory test determines whether slow-growing mycobacteria (such as certain types of tuberculosis or non-tuberculous mycobacteria) are sensitive or resistant to the antibiotic combination of amoxicillin and clavulanate.

Quick summary

{"This test checks if antibiotics can effectively treat a mycobacterial infection","Results help doctors choose the right antibiotics for your treatment","The test is performed on a sample of your blood (serum)","Results typically take several days to weeks because mycobacteria grow slowly"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25310-4
Short code
Amoxicillin+Clav Islt SlowMyco
Synonyms
Amoxicillin+Clav Islt SlowMyco
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
method-for-slow-growing-mycobacteria
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test, what exactly does it measure or look for in my body, and why is it considered a useful tool for evaluating my overall health?

The Amoxicillin/Clavulanate Susceptibility Test is a laboratory test that determines how well the antibiotic combination of amoxicillin and clavulanate works against slow-growing mycobacteria. Mycobacteria are a type of bacteria that cause infections like tuberculosis (TB) and certain other less common infections. These bacteria grow very slowly in laboratory conditions, which is why special testing methods are required.

How is this test performed, what steps are involved in the procedure, and what should I expect when I arrive for my appointment?

A blood sample is collected from you and sent to a laboratory. In the lab, scientists grow the mycobacteria from your sample and then expose them to amoxicillin/clavulanate to see if the bacteria are killed or inhibited. This process helps determine if the antibiotic will be effective in treating your infection. Because mycobacteria grow slowly, this test may take several days to weeks to complete.

Why might I need this test, and in what situations would my healthcare provider recommend it as part of my care or diagnosis?

Your doctor may order this test if you have a confirmed or suspected infection with slow-growing mycobacteria, such as Mycobacterium tuberculosis or non-tuberculous mycobacteria (NTM). The results help your doctor choose the most appropriate antibiotic treatment, as some mycobacteria are naturally resistant to certain antibiotics. This test is particularly important for treating persistent or difficult-to-cure infections.

What do the results of this test mean, how are normal and abnormal values interpreted, and what are the next steps after I receive my results?

The test result will indicate whether the mycobacteria are 'susceptible' (sensitive) or 'resistant' to amoxicillin/clavulanate. If the bacteria are susceptible, the antibiotic combination is likely to be effective in treating your infection. If the bacteria are resistant, your doctor will need to choose different antibiotics. Your doctor will interpret these results in the context of your overall health and infection status.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This susceptibility test is crucial for guiding appropriate antibiotic therapy in mycobacterial infections. Slow-growing mycobacteria, including Mycobacterium tuberculosis and various non-tuberculous mycobacteria, can be resistant to many standard antibiotics. Testing helps identify which antibiotics will be most effective, reducing treatment failure and preventing the development of antibiotic resistance. The amoxicillin/clavulanate combination is particularly useful because clavulanate inhibits beta-lactamase enzymes that some bacteria produce to destroy antibiotics.

Frequently asked questions

Is the test painful?
The test requires a simple blood draw, which may cause brief discomfort or a minor bruise at the needle site. The procedure is generally well-tolerated and takes only a few minutes.
How long does it take to get results?
Results typically take longer than standard blood tests because slow-growing mycobacteria require several days to weeks to grow in the laboratory. Your doctor will inform you when results are available.
Do I need to fast before this test?
No special preparation, including fasting, is usually required for this test. Follow any specific instructions provided by your healthcare provider.
What happens after I get my results?
Your doctor will discuss the results with you and determine the most appropriate treatment plan based on the susceptibility results and your individual medical condition.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy