Blood Test (Laboratory Blood Test): What It Is, Why It Is Done, and What Your Results Mean
This test detects specific resistance genes in bacteria that can make certain antibiotics less effective.
{"Detects genes that cause resistance to beta-lactam antibiotics like cephalosporins","Helps doctors choose the right antibiotic for treatment","Uses a molecular method to identify genetic markers of resistance","Results indicate whether specific resistance genes are present or absent","Important for treating serious bacterial infections effectively"}
Key facts at a glance
- LOINC
- 85822-5
- Short code
- AmpC blaCMY+blaMOX genes Islt/Spm Ql
- Synonyms
- AmpC blaCMY+blaMOX genes Islt/Spm Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
A blood test is a common laboratory analysis that measures different components of your blood, such as red and white blood cells, platelets, glucose, electrolytes, hormones, or cholesterol. Your doctor uses these measurements to check how well your organs are working, to screen for certain diseases, or to monitor a condition you already have. It is one of the most routine and informative tools in modern medical care.
This test looks for specific genes called blaCMY and blaMOX in bacteria. These genes produce enzymes called AmpC beta-lactamases that can break down and inactivate certain antibiotics called beta-lactams, which include penicillins and cephalosporins. When these genes are present, the bacteria become resistant to many commonly used antibiotics.
Your doctor may order this test as part of a routine checkup, to help find the cause of symptoms such as fatigue, fever, or unexplained weight loss, to confirm or rule out a diagnosis, or to track how well a treatment or medication is working over time. Changes in blood values can sometimes signal a health problem before you notice any symptoms, which makes the test valuable for early detection.
Your doctor may order this test if you have a bacterial infection that is not responding to standard antibiotic treatment. By detecting these resistance genes, your healthcare team can determine which antibiotics will work best against your infection. This is especially important for serious infections like bloodstream infections, pneumonia, or urinary tract infections.
The test is performed by a trained healthcare professional, usually a nurse or phlebotomist, who draws a small sample of blood from a vein, most often on the inside of your elbow or the back of your hand. The site is cleaned with an antiseptic, an elastic band is placed around your upper arm, and a thin needle collects the sample into one or more tubes. The procedure usually takes only a few minutes and may cause brief, mild discomfort or slight bruising afterward.
A blood sample (serum) is collected from you and sent to a laboratory. Scientists use molecular techniques, specifically polymerase chain reaction (PCR), to detect the presence of the blaCMY and blaMOX genes in the sample. This method is highly sensitive and can identify even small amounts of genetic material from resistant bacteria.
Your results are compared with reference ranges, which show the values typically seen in healthy people. Results within these ranges are generally considered normal, while values that are higher or lower than expected may point to conditions such as infection, inflammation, anemia, dehydration, or blood sugar problems that may need further testing or follow-up. Your doctor will interpret the numbers together with your symptoms, medications, and medical history, because a single abnormal value does not always mean you are ill. Always review your results with your healthcare provider to understand exactly what they mean for your health.
The test result will show whether the blaCMY and/or blaMOX genes are detected (positive) or not detected (negative). A positive result means the bacteria causing your infection carry these resistance genes and may not respond to certain beta-lactam antibiotics. A negative result suggests these specific resistance genes are not present, though other resistance mechanisms may still exist.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Detection of blaCMY and blaMOX genes is clinically significant because it helps guide antibiotic selection. AmpC-producing bacteria are resistant to many commonly prescribed antibiotics including ampicillin, amoxicillin, cephalothin, and some cephalosporins. This information helps clinicians choose alternative antibiotics that will be effective, improving patient outcomes and reducing the spread of antibiotic-resistant infections.
This test is particularly important in hospital settings where antibiotic-resistant infections are more common. It contributes to antimicrobial stewardship programs aimed at preserving the effectiveness of existing antibiotics and preventing the development of further resistance.
Frequently asked questions
Is this test painful?
How long does it take to get results?
Do I need to fast before this test?
What happens if my test is positive?
Can these resistance genes spread to other people?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy