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Understanding Your Laboratory Test: What It Is and Why Your Doctor Ordered It

Published: August 9, 2026Updated: August 16, 2026

This test detects amphetamine and methamphetamine exposure in newborns through meconium sample analysis.

Quick summary

{"This test checks if a newborn was exposed to amphetamine-type drugs before birth","Meconium (the baby's first stool) is used as the sample because it accumulates drug metabolites over time","A positive result helps healthcare providers identify and address potential health concerns early","The test uses confirmatory methods for high accuracy","Results are confidential and used for medical care rather than legal purposes"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
69021-4
Short code
Amphetamines Pnl Mec Cfm
Synonyms
Amphetamines Pnl Mec Cfm
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test, and why might my doctor recommend it for me?

The Amphetamines Panel Test (Meconium) is a laboratory test that checks whether a newborn baby has been exposed to amphetamine or methamphetamine while in the womb. Unlike blood or urine tests that show recent drug use, meconium testing can detect drug exposure that occurred during the later stages of pregnancy, typically from about 20 weeks gestation until birth.

How does the test work, and what does it measure in my body?

Meconium is the dark, sticky first stool that a newborn passes. It forms during pregnancy and can accumulate drug metabolites (breakdown products) that cross the placenta from the mother's bloodstream. The test uses a confirmatory method called mass spectrometry, which is highly accurate and specific for identifying amphetamine and methamphetamine.

What happens during sample collection, and how should I prepare for it?

Sample collection is simple and non-invasive. Meconium is collected from the baby's diaper shortly after birth, usually within the first 24-72 hours of life. The sample is placed in a special container and sent to a laboratory for testing. No blood draw or painful procedure is required for the baby.

What do my results mean, and what should I do once I receive them?

A negative result means no amphetamines were detected in the meconium sample. A positive result indicates that the baby was exposed to amphetamines during pregnancy. It's important to note that a positive result does not necessarily mean the mother used drugs—it could indicate environmental exposure. Healthcare providers use these results along with other clinical information to determine the best care plan for the baby.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is primarily used in newborn screening programs to identify infants who may have been exposed to amphetamine-type stimulants during pregnancy. Early identification allows healthcare providers to monitor for potential complications such as neonatal abstinence syndrome (NAS), growth problems, developmental delays, or other health issues. Early intervention and appropriate care can significantly improve outcomes for affected infants. The test is also valuable for identifying cases where the mother may need substance abuse treatment and support services.

Frequently asked questions

Will this test be used to report me to law enforcement?
No. This is a medical test designed solely for healthcare purposes. Results are part of the baby's medical record and are used to provide appropriate medical care. Healthcare providers are not required to report positive results to law enforcement, though they may offer resources and support for families dealing with substance use issues.
How accurate is this test?
The confirmatory method used (typically mass spectrometry) is very accurate and specific. It can reliably distinguish between amphetamines and other substances. However, like all tests, there is a small possibility of false positives or negatives. If the result is unexpected, your healthcare provider may recommend additional testing or evaluation.
What if my baby tests positive?
If the test is positive, your healthcare team will discuss the results with you and develop an appropriate care plan. This may include additional monitoring, supportive care, or referrals to specialists. The goal is to ensure the best possible health outcomes for your baby. Many hospitals have support services available to help families in this situation.
Can environmental exposure cause a positive result?
It is possible for a baby to test positive if the mother was exposed to second-hand amphetamine smoke or certain medications containing amphetamine-like compounds. Your healthcare provider will consider all factors when interpreting the results.
How long does it take to get results?
Test results typically take several days to a week, depending on the laboratory. The confirmatory testing process is more thorough than initial screening tests, which ensures accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy