Understanding Your Laboratory Test: What It Is and Why Your Doctor Ordered It
This test detects amphetamine and methamphetamine exposure in newborns through meconium sample analysis.
{"This test checks if a newborn was exposed to amphetamine-type drugs before birth","Meconium (the baby's first stool) is used as the sample because it accumulates drug metabolites over time","A positive result helps healthcare providers identify and address potential health concerns early","The test uses confirmatory methods for high accuracy","Results are confidential and used for medical care rather than legal purposes"}
Key facts at a glance
- LOINC
- 69021-4
- Short code
- Amphetamines Pnl Mec Cfm
- Synonyms
- Amphetamines Pnl Mec Cfm
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- confirm
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test, and why might my doctor recommend it for me?
The Amphetamines Panel Test (Meconium) is a laboratory test that checks whether a newborn baby has been exposed to amphetamine or methamphetamine while in the womb. Unlike blood or urine tests that show recent drug use, meconium testing can detect drug exposure that occurred during the later stages of pregnancy, typically from about 20 weeks gestation until birth.
How does the test work, and what does it measure in my body?
Meconium is the dark, sticky first stool that a newborn passes. It forms during pregnancy and can accumulate drug metabolites (breakdown products) that cross the placenta from the mother's bloodstream. The test uses a confirmatory method called mass spectrometry, which is highly accurate and specific for identifying amphetamine and methamphetamine.
What happens during sample collection, and how should I prepare for it?
Sample collection is simple and non-invasive. Meconium is collected from the baby's diaper shortly after birth, usually within the first 24-72 hours of life. The sample is placed in a special container and sent to a laboratory for testing. No blood draw or painful procedure is required for the baby.
What do my results mean, and what should I do once I receive them?
A negative result means no amphetamines were detected in the meconium sample. A positive result indicates that the baby was exposed to amphetamines during pregnancy. It's important to note that a positive result does not necessarily mean the mother used drugs—it could indicate environmental exposure. Healthcare providers use these results along with other clinical information to determine the best care plan for the baby.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is primarily used in newborn screening programs to identify infants who may have been exposed to amphetamine-type stimulants during pregnancy. Early identification allows healthcare providers to monitor for potential complications such as neonatal abstinence syndrome (NAS), growth problems, developmental delays, or other health issues. Early intervention and appropriate care can significantly improve outcomes for affected infants. The test is also valuable for identifying cases where the mother may need substance abuse treatment and support services.
Frequently asked questions
Will this test be used to report me to law enforcement?
How accurate is this test?
What if my baby tests positive?
Can environmental exposure cause a positive result?
How long does it take to get results?
Sources
- 1
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Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy