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Understanding Your Medical Test: What It Means for Your Health

Published: August 9, 2026Updated: August 16, 2026

A blood test that checks for the presence of amphetamine-type stimulant drugs in your system.

Quick summary

{"This test detects amphetamine and related stimulant drugs in blood","It is used to monitor medication use or check for drug abuse","A positive result means these substances were found in your blood"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
8149-7
Short code
Amphetamines SerPl Ql Scn
Synonyms
Amphetamines SerPl Ql Scn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test is a laboratory procedure that gives your healthcare provider important information about your health by analyzing a sample collected from your body, helping to evaluate how well your organs and body systems are functioning.

The Amphetamine Screen is a blood test that looks for the presence of amphetamine-type stimulants in your bloodstream. These drugs include amphetamine, methamphetamine, MDMA (ecstasy), and related substances. The test does not measure how much of the drug is in your blood—it simply shows whether these substances are present or not (positive or negative result).

Your doctor may order this test to help diagnose a medical condition, find the cause of symptoms you are having, screen for possible health risks, check how well a treatment is working, or monitor an ongoing condition over time.

Your healthcare provider may order this test for several reasons: (1) to monitor patients taking prescription stimulant medications like Adderall or Desoxyn for conditions such as ADHD or narcolepsy; (2) to check for drug abuse or misuse; (3) as part of a workplace or athletic drug screening program; (4) in emergency settings when drug intoxication is suspected; or (5) during substance abuse treatment programs to ensure compliance with treatment goals.

The test is usually done in a clinic, hospital, or laboratory. A trained healthcare professional will collect the needed sample after following any preparation instructions you were given, and the sample is then sent to a laboratory for analysis.

A healthcare professional will draw a small sample of blood from a vein in your arm. The blood sample will be sent to a laboratory for analysis. You do not need to fast or prepare specially for this test, unless your healthcare provider gives you specific instructions.

Your results will be compared with standard reference ranges used by the laboratory. A value outside the normal range does not always mean you are ill, so your healthcare provider will review your results with you, explain what they mean, and discuss any next steps.

A negative result means no amphetamine-type substances were detected in your blood at the time of testing. A positive result indicates that these substances were found. If you are taking a prescribed stimulant medication, a positive result is expected and shows that the medication is in your system. However, if you are not prescribed these medications, a positive result may indicate undisclosed use of these drugs. Your healthcare provider will discuss what your specific results mean for your situation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is clinically important for multiple purposes. In therapeutic monitoring, it helps ensure patients taking prescribed stimulants have the medication in their system as expected. For substance abuse detection, it can identify use of illicit stimulants. In emergency medicine, it helps diagnose acute intoxication or overdose. The test is also valuable in occupational health settings and rehabilitation programs. It is important to note that this is a screening test—positive results may sometimes require confirmatory testing with more specific methods to identify exactly which substance was present.

Frequently asked questions

How long do amphetamines stay in your blood?
Amphetamines can typically be detected in blood for about 12-24 hours after use, though this varies depending on the specific substance, dosage, individual metabolism, and frequency of use. Longer-term or chronic use may result in detection for longer periods.
Will a positive result show which specific drug I took?
This is a screening test that detects the general class of amphetamine-type stimulants. If the result is positive and more specific identification is needed, your healthcare provider may order a confirmatory test that can identify the exact substance.
Can my prescription medication cause a positive result?
Yes. Legally prescribed stimulant medications such as amphetamine (Adderall), methamphetamine (Desoxyn), or methylphenidate (Ritalin, Concerta) will cause a positive result. It is important to inform the testing facility and your healthcare provider about all prescription medications you are taking before the test.
Do I need to fast before this test?
No fasting is typically required for this blood test. You can eat and drink normally before having your blood drawn, unless your healthcare provider instructs otherwise.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy