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Amphetamine Urine Test: What It Is, How It Works, and What Your Results Mean

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of amphetamines (stimulant drugs) in a urine sample using the SAMHSA-approved screening method.

Quick summary

{"A simple urine test that detects amphetamine use","Results are typically available within 1-3 days","Commonly used for workplace, legal, or medical screening purposes","A positive result may require confirmatory testing","Certain medications and foods can affect results"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
8152-1
Short code
Amphetamines Ur Ql SAMHSA Scn
Synonyms
Amphetamines Ur Ql SAMHSA Scn
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
samhsa-screen
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is an amphetamine urine test and why might my doctor order it for me?

The Amphetamines Urine Drug Test is a screening test that detects the presence of amphetamine-type stimulant drugs in your urine. Amphetamines include illegal drugs like methamphetamine (speed, crystal meth) and prescription medications such as Adderall, Dexedrine, and some ADHD medications. This test uses the SAMHSA (Substance Abuse and Mental Health Services Administration) standardized method, which is the same protocol used for federally-mandated workplace drug testing in the United States.

How is the amphetamine urine test performed, and do I need to do anything to prepare?

You will be asked to provide a urine sample in a clean container. The collection process is similar to a routine urine test. For workplace or legal testing, the collection may be observed to ensure sample integrity. The sample is then sent to a laboratory where it is analyzed using immunoassay techniques to detect amphetamine compounds. If the initial screen is positive, a confirmatory test (GC-MS or LC-MS/MS) is typically performed to verify the result.

How long do amphetamines stay in urine after the last time they were used?

Amphetamines can typically be detected in urine for 1-4 days after use, depending on factors such as the specific drug, dosage, frequency of use, individual metabolism, body mass, and kidney function. Chronic or heavy use may result in longer detection windows.

What do my amphetamine urine test results mean if they come back positive or negative?

A 'negative' result means no amphetamines were detected at or above the testing threshold. A 'positive' result indicates that amphetamines were detected and requires confirmatory testing. It's important to note that certain prescription medications (such as ADHD medications) and some over-the-counter drugs may cause a positive result. Always disclose all medications you are taking to the testing facility.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Will I know if I pass or fail before the test?
No. This is a laboratory-based test that requires professional analysis. Home instant tests are available but are not SAMHSA-compliant and may not be accepted for official testing purposes.
Can my prescription medication cause a positive result?
Yes. Legitimate prescriptions for ADHD medications (Adderall, Ritalin, Vyvanse), certain antidepressants, and other medications may cause a positive amphetamine result. Always inform the testing collector about all prescription and over-the-counter medications you are taking.
Can certain foods cause a positive result?
Some false positives have been reported from certain foods, supplements, or poppy seeds, though this is less common with modern testing methods. However, the confirmatory test can distinguish between actual amphetamines and these substances.
What happens if I test positive?
A positive screening result requires confirmatory testing. If the confirmatory test is also positive, the result is considered verified. The consequences of a positive result depend on why you were tested (employment, legal, or medical reasons). You may have the opportunity to explain any legitimate medical use.
How long does it take to get results?
Results are typically available within 1-3 business days, though this may vary depending on the testing facility and whether confirmatory testing is needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy