Skip to content

Understanding Your Laboratory Test: A Patient Guide to Testing, Results, and Follow-Up Care

Published: August 9, 2026Updated: August 16, 2026

A urine test that detects the presence of amphetamines and related stimulant drugs in your system.

Quick summary

{"This test screens for amphetamine-type stimulants including methamphetamine and MDMA","It is commonly used for workplace drug testing, legal/probation monitoring, and medical evaluation","A positive result may indicate recent use but does not measure impairment or amount used","Results should be confirmed with a more specific test like GC/MS if needed","Certain prescription medications and supplements may cause false positive results"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
70138-3
Short code
Amphetamines Ur Scn-mCnc
Synonyms
Amphetamines Ur Scn-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

This test is a laboratory analysis, usually performed on a small sample of your blood, urine, or other body fluid, that helps your healthcare provider evaluate how well your body is functioning and look for signs of illness, infection, or other abnormal conditions.

The Amphetamine Urine Screening Test is a laboratory test that detects the presence of amphetamine-type stimulants in a urine sample. These drugs include amphetamine, methamphetamine (commonly known as meth), MDMA (ecstasy), and related compounds. The test uses an immunoassay screening method to quickly identify whether these substances or their metabolites are present in your urine.

Your provider may order this test as part of a routine checkup, to help diagnose the cause of symptoms you are experiencing, to screen for a condition before it causes noticeable problems, or to monitor how well a treatment or an ongoing medical condition is being managed over time.

Healthcare providers may order this test for several reasons: workplace or pre-employment drug screening, monitoring for compliance with legal or probation requirements, evaluating patients with symptoms of stimulant use or overdose, preoperative assessment before surgery, or monitoring patients in substance abuse treatment programs. It may also be ordered if your doctor suspects accidental or intentional overdose of stimulant medications.

The test is typically done in a clinic, hospital, or laboratory. A trained professional will collect the needed sample, for example by drawing a small amount of blood from a vein in your arm or asking you to provide a urine sample, and then send it to the lab for analysis. The procedure is quick, and most people can return to their normal activities right away.

You will be asked to provide a urine sample in a clean container. The collection process is similar to a routine urine test. For workplace or legal testing, the collection may be observed to ensure sample integrity. The sample is then sent to a laboratory where it is analyzed using immunoassay techniques that detect amphetamine compounds and their metabolites. The entire process is quick and painless.

Your results are compared with reference ranges, which are typical values seen in healthy people. Results within the normal range usually suggest no abnormality, while values that are too high or too low may point to a condition that needs further evaluation. Your provider will review the numbers with you, explain what they mean in the context of your overall health, and discuss any follow-up testing or treatment that may be needed.

Results are typically reported as either 'Negative' (no amphetamines detected) or 'Positive' (amphetamines detected above the cutoff threshold). A negative result generally means no amphetamines were found in your urine at the time of testing. A positive result indicates that amphetamines or related substances were detected. However, a positive screening test is considered preliminary and should be confirmed with a more specific confirmatory test like Gas Chromatography-Mass Spectrometry (GC/MS) to verify the exact substance and rule out false positives.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is primarily used for screening purposes in occupational health, legal/court-ordered testing, and substance abuse monitoring programs. A positive result can help identify recent use of stimulant medications or illicit drugs, which may be important for patient care, workplace safety, or legal compliance. In clinical settings, it may help diagnose acute intoxication or overdose. However, the test does not indicate when the drug was taken, the amount used, or whether a person is currently impaired. Certain prescription medications (such as some ADHD treatments, decongestants, and antidepressants) and even some dietary supplements can cause false positive results, which is why confirmatory testing is important.

Frequently asked questions

How long do amphetamines stay in urine?
Amphetamines can typically be detected in urine for 1-3 days after use, though this varies depending on factors like the specific drug, dose, frequency of use, individual metabolism, kidney function, and urine pH. Chronic heavy use may result in detection for longer periods.
Can a positive result occur from prescription medications?
Yes. Certain prescription medications can cause a positive amphetamine screen. These include stimulant medications for ADHD (like Adderall, Ritalin), some nasal decongestants, and certain antidepressants. It is important to inform the testing facility of all medications you are taking. A confirmatory test can help distinguish between illegal drug use and legitimate prescription use.
Will a positive test show if I am currently impaired?
No. This test only indicates whether amphetamines or their metabolites are present in your urine. It does not measure current impairment or intoxication. The effects of amphetamines typically wear off long before the drug can be detected in urine.
What is a confirmatory test and why might I need one?
A confirmatory test, typically using Gas Chromatography-Mass Spectrometry (GC/MS), is a more sophisticated laboratory test that can precisely identify and quantify specific amphetamine compounds. It is used when a screening test is positive to verify the result, rule out false positives, and determine exactly which substance was detected. Confirmatory tests are often required for legal or workplace testing contexts.
Can diet or lifestyle affect the test results?
Certain dietary supplements containing precursors to amphetamines or herbal products may potentially cause positive results. It is important to disclose all supplements and over-the-counter medications to your healthcare provider. Drinking large amounts of water before the test will not affect the detection of drugs, though it may dilute the sample.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy