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Amphetaminesvitfql

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of amphetamine-type stimulants in the vitreous fluid of the eye, used to identify recent drug use.

Quick summary

{"Detects amphetamine and related stimulant drugs in eye fluid","Helps confirm drug exposure when other tests are unavailable","Used in clinical toxicology and forensic investigations"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27205-4
Short code
Amphetamines Vitf Ql
Synonyms
Amphetamines Vitf Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

The Amphetamines test is a toxicology test that detects the presence of amphetamine-type stimulant drugs in the vitreous fluid—the clear, gel-like substance inside the eye. This test uses a qualitative (presence/absence) method to determine whether amphetamines or related substances are present in the sample.

How is the sample collected?

The sample is collected from the vitreous cavity of the eye using a fine needle in a procedure called vitreous aspiration. This is typically performed by an ophthalmologist or trained medical professional. The procedure is done under sterile conditions to minimize risks.

Why is vitreous fluid used instead of blood or urine?

Vitreous fluid can be useful when blood or urine samples are not available. It may provide a longer detection window for certain drugs and can be particularly valuable in postmortem investigations or when other sample types are contaminated or inaccessible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings2

Frequently asked questions

What drugs does this test detect?
This test detects amphetamine and related stimulant drugs including methamphetamine, MDMA (ecstasy), and other amphetamine-type substances. The specific compounds detected depend on the test method used.
How long after use can these drugs be detected?
Detection windows in vitreous fluid may be longer than in blood or urine, potentially ranging from several days to weeks, depending on the drug, dose, and individual factors.
Is this test painful?
The vitreous aspiration procedure is performed under local anesthesia, so discomfort is minimal. There may be mild irritation afterward, and there is a small risk of infection or bleeding.
Do I need to prepare for this test?
No special preparation is needed. Your healthcare provider will explain the procedure and obtain your consent before sample collection.
  1. 1
    MedlinePlus - Drug TestingSource
  2. 2
    Mayo Clinic Laboratories - Toxicology TestsSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy