Your Laboratory Test: A Patient's Guide to Testing, Sample Collection, and Results
A confirmatory test to detect amphetamines in saliva, used to verify presence of stimulant drugs.
{"This test checks for amphetamine-type drugs in your saliva","It uses a confirmatory method (like mass spectrometry) for accurate results","Commonly used for workplace drug testing or medical evaluation","Sample is collected via oral fluid (spit) not blood","Results show if drug level is above or below the testing cutoff"}
Key facts at a glance
- LOINC
- 78364-7
- Short code
- Amphet CtO Sal Cfm-mCnc
- Synonyms
- Amphet CtO Sal Cfm-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- confirm
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
A laboratory test is a procedure in which a sample of your blood, urine, or other body fluid or tissue is analyzed to help your doctor evaluate your overall health, screen for disease, diagnose symptoms, or monitor a condition you may already have.
The Amphetamine Confirmatory Saliva Test is a laboratory test that detects the presence of amphetamine-type stimulant drugs in your saliva (also called oral fluid). Unlike screening tests, this confirmatory test uses highly accurate methods like mass spectrometry to precisely identify and measure amphetamine compounds. This test is typically used to verify positive screening results or when definitive proof of drug use is required.
Your sample is usually collected at a clinic, hospital, or laboratory. A trained professional may draw blood from a vein in your arm, ask you to provide a urine sample, or take a swab from the area being tested, depending on what your doctor has ordered.
A saliva sample is collected by placing a special collection device in your mouth to absorb oral fluid. The process is quick, non-invasive, and does not require blood draw. You may be asked to not eat, drink, smoke, or chew gum for a certain period before sample collection to ensure accurate results.
Your doctor may order this test as part of a routine checkup, to help find the cause of symptoms you are having, to screen for certain conditions before they cause problems, or to see how well a treatment is working over time.
This test may be ordered for various reasons including: workplace drug testing programs, legal or forensic investigations, substance abuse monitoring, pre-employment screening, or as part of a comprehensive drug evaluation when a screening test shows a preliminary positive result.
Your results are compared with a reference range, which is the range of values typically seen in healthy people. A value outside this range does not always mean you are ill, so review your results with your doctor, who can explain what they mean for you.
This is a cutoff-based test (qualitative). Results are typically reported as either 'detected' (above the cutoff/threshold) or 'not detected' (below the cutoff). A 'detected' result means amphetamine or related substances were found at levels above the testing threshold. The specific cutoff value may vary by laboratory. A confirmatory positive result provides strong evidence of amphetamine use.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
The confirmatory saliva test for amphetamines is clinically significant because it provides legally defensible, high-accuracy results. It helps differentiate between true amphetamine use and false-positive screening results from medications or food. In clinical settings, it assists in diagnosing stimulant use disorders, monitoring treatment compliance for prescribed stimulants (like ADHD medications), and evaluating patients with suspected drug intoxication. In occupational and legal contexts, it meets strict chain-of-custody requirements for drug-free workplace programs.
Frequently asked questions
How long can amphetamines be detected in saliva?
Will I test positive if I take ADHD medication?
Can passive exposure cause a positive result?
How long does it take to get results?
Is fasting required before the test?
Sources
- 1
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Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy