Understanding Your Medical Test: A Patient Guide to What It Is, Why It Is Done, and What to Expect
This test detects the presence of amphetamine and methamphetamine in your blood to monitor medication use or screen for illegal drug exposure.
{"This test checks for stimulants like amphetamine and methamphetamine in your blood","It is used to monitor prescription ADHD medications or detect illegal drug use","Results are confirmed using specialized laboratory methods","A positive result may have legal and employment implications","The test requires a blood sample drawn from a vein"}
Key facts at a glance
- LOINC
- 75644-5
- Short code
- Amphet+Methamphet Bld Ql Cfm
- Synonyms
- Amphet+Methamphet Bld Ql Cfm
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- confirm
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
This test is a medical procedure that helps your healthcare provider check how your body is working. It can be used to look for signs of disease, confirm or rule out a diagnosis, or keep track of a condition you already have. Your provider will explain what the test measures and how it fits into your overall care plan.
The Amphetamine/Methamphetamine blood test is a confirmatory laboratory test that detects whether amphetamine and methamphetamine are present in your bloodstream. These are stimulant drugs that affect the central nervous system. The test uses sophisticated methods to accurately identify and confirm the presence of these substances.
You may need this test if you have symptoms that need a closer look, if you are due for routine screening, or if you have a condition that requires regular monitoring. It can also help your provider choose a treatment, check whether your current treatment is working, or watch for possible side effects over time.
Your healthcare provider may order this test for several reasons: to monitor proper use of prescription stimulant medications (such as those used to treat ADHD or narcolepsy), to verify abstinence from illegal stimulant drugs as part of a treatment program, for pre-employment or legal drug screening, or to investigate symptoms that may be related to drug use or overdose.
How the test is performed depends on the type ordered, but most tests are simple and done in an office, clinic, or hospital by trained staff. You may be asked to prepare in advance, such as fasting or pausing certain medicines. The test itself is usually quick, and your care team will guide you through each step and answer your questions.
A healthcare professional will draw a small sample of blood from a vein in your arm using a needle. The blood sample is then sent to a laboratory where it undergoes confirmatory testing using specialized techniques that can accurately identify and measure the presence of amphetamine and methamphetamine.
Your results show whether your values fall within the normal range for this test. Normal results can be reassuring, while abnormal results do not always mean something serious. Your provider will review the results with you, explain what they mean in the context of your overall health, and discuss any follow-up testing or treatment that may be needed.
A 'negative' result means no amphetamine or methamphetamine was detected in your blood at the time of testing. A 'positive' result indicates that these substances were found in your blood. If you have a valid prescription for a medication containing these drugs, inform your healthcare provider and bring your prescription documentation. Results may remain positive for several days after use, depending on the specific substance and individual metabolism.
Most people have this test without any problems, and serious complications are rare. Depending on the type of test, you might have brief discomfort, minor bruising, or slight bleeding where a needle was inserted. The risk of infection is very low. Tell your provider about allergies, bleeding problems, or medicines you take, and ask questions if you have concerns.
The risks associated with this blood test are minimal and include slight bruising at the puncture site, bleeding, or rarely, infection. These risks are similar to routine blood draws.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is clinically significant for monitoring compliance with prescription stimulant therapies, detecting intentional or accidental overdose of stimulant medications, identifying illicit methamphetamine or amphetamine use, and supporting addiction treatment programs. It may also be used in forensic or legal contexts where documentation of drug exposure is required. Positive results should be interpreted in conjunction with clinical history, prescription records, and physical examination findings.
Frequently asked questions
How long do these drugs stay in my blood?
Will a positive result show up on my medical record?
Can ADHD medications cause a positive result?
What happens if I test positive for illegal drugs?
Can second-hand exposure cause a positive result?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy