Skip to content

Complete Blood Count (CBC) Test: What It Is and Why It Is Done

Published: August 9, 2026Updated: August 16, 2026

This test checks whether amphetamine or methamphetamine is present in your blood sample.

Quick summary

{"Detects stimulant drugs in blood for monitoring or screening purposes","Used to verify proper medication use or detect drug abuse","Sample is collected via blood draw","Results are reported as positive or negative (presence only)"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40421-0
Short code
Amphet+Methamphet SerPl Ql
Synonyms
Amphet+Methamphet SerPl Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test? A complete blood count, or CBC, is a common blood test that measures the different cells in your blood, including red blood cells, white blood cells, and platelets, to help evaluate your overall health.

The Amphetamine/Methamphetamine test is a laboratory test that detects the presence of stimulant drugs in your blood (serum or plasma). It looks for traces of amphetamine and methamphetamine—two related stimulant substances that affect the central nervous system. The test does not measure how much of the drug is in your system, only whether it is detectable.

Why might I need this test? Your provider may order a CBC as part of a routine checkup, or to help find the cause of symptoms such as fatigue, weakness, fever, easy bruising, or unusual bleeding, and to monitor conditions like anemia or infection.

Your healthcare provider may order this test for several reasons: to monitor patients taking prescription stimulant medications (such as those for ADHD or narcolepsy) and ensure they are taking the correct dose; to screen for illegal or non-prescribed use of stimulants; as part of workplace or forensic drug testing programs; or to help diagnose suspected drug poisoning or overdose. The test helps your doctor understand your exposure to these substances.

How is the test performed? A health care professional will clean your skin, wrap a band around your upper arm, and draw a small sample of blood from a vein, usually in your arm; the sample is then sent to a laboratory for analysis.

A healthcare professional will draw a small sample of blood from a vein in your arm using a needle. The blood sample is then sent to a laboratory where it is analyzed using specialized equipment to detect the presence of amphetamine or methamphetamine. You do not need to fast or make any special preparations before this test, unless your doctor instructs otherwise.

What do the results mean? Your results show whether your red blood cell, white blood cell, and platelet counts fall within the normal range; values that are too high or too low can point to conditions such as anemia, infection, inflammation, or clotting problems, and your provider will explain what they mean for you.

Results are typically reported as either 'Positive' (drug detected) or 'Negative' (no drug detected). A positive result means amphetamine, methamphetamine, or related substances were found in your blood at the time of testing. Your doctor will interpret the result based on your medical history, medications, and the reason for testing. It is important to inform your healthcare provider about all prescription medications, over-the-counter drugs, and supplements you are taking, as some substances may affect the test results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test has important clinical applications in monitoring medication compliance for patients prescribed stimulant therapies, detecting intentional or unintentional drug overdose, and screening for substance abuse in clinical and forensic settings. Amphetamines are legitimate prescription medications used to treat conditions like attention deficit hyperactivity disorder (ADHD) and narcolepsy, while methamphetamine is a highly addictive illegal drug with severe health risks. A positive result requires careful clinical interpretation considering the patient's known prescriptions and medical circumstances. The test may also help identify drug interactions or verify that therapeutic drug levels are being maintained.

Frequently asked questions

How long do these drugs stay in my blood?
Amphetamine and methamphetamine can typically be detected in blood for about 24 to 48 hours after use, though this varies depending on factors like dosage, individual metabolism, kidney function, and the specific substance used. Chronic or heavy use may result in longer detection times.
Can my prescription medication cause a positive result?
Yes. Certain prescription and over-the-counter medications contain amphetamine-like compounds or may cross-react with the test. Always inform your doctor and the testing laboratory about all medications you are taking, including ADHD medications (like Adderall or Ritalin), cold medicines, diet pills, and herbal supplements.
Do I need to prepare for the test?
Generally, no special preparation is needed. You can eat and drink normally before the test. However, follow any specific instructions provided by your healthcare provider. It is important to disclose all medications and substances you have recently used.
Is the test confidential?
Yes, laboratory test results are protected by privacy laws and are part of your confidential medical record. Results will be shared only with your healthcare provider and others you authorize to receive them, unless required by law.
What happens if my test is positive?
If your test is positive, your healthcare provider will discuss the result with you. They will consider your known medical conditions, current prescriptions, and the reason for testing. A positive result does not necessarily mean illegal drug use—it may indicate proper use of a prescribed medication or exposure to certain substances.
  1. 1
  2. 2

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy