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Amphetmethamphetspecql

Published: August 9, 2026Updated: August 16, 2026

This test checks whether amphetamine or methamphetamine drugs are present in your blood sample.

Quick summary

{"The test detects stimulant drugs like amphetamines and methamphetamines in your blood","It is used for drug screening, medication monitoring, or clinical diagnosis","Results are reported as positive or negative (presence only)","Certain medications and foods may affect test results","Always inform your doctor about all medications you are taking"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40420-2
Short code
Amphet+Methamphet Spec Ql
Synonyms
Amphet+Methamphet Spec Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

The Amphetamine and Methamphetamine test is a laboratory test that detects the presence of stimulant drugs in your blood serum. Amphetamines are a class of drugs that stimulate the central nervous system, including prescription medications (like Adderall, Dexedrine) and illicit substances (like methamphetamine/crystal meth). This test looks for whether these substances are present in your bloodstream.

Why might I need this test?

Your doctor may order this test for several reasons: (1) Drug screening — to check for illegal or non-prescribed drug use, often required for employment, sports, or legal reasons; (2) Medication monitoring — to ensure proper levels if you are prescribed amphetamine medications for conditions like ADHD or narcolepsy; (3) Medical evaluation — if you have symptoms of drug overdose or toxicity; (4) Forensic purposes — in cases involving accidents or legal investigations.

How is the test performed?

A healthcare professional will draw a small amount of blood from a vein in your arm using a needle. This blood sample will be sent to a laboratory for analysis. The test uses specialized equipment to detect whether amphetamine or methamphetamine substances are present in your serum. No special preparation is typically needed, but follow any specific instructions from your doctor.

Understanding your results

Results are typically reported as 'Positive' (drug detected) or 'Negative' (no drug detected). A positive result means amphetamine or methamphetamine was found in your blood. A negative result means no amphetamines were detected above the test's detection threshold. Your doctor will interpret the results in the context of your medical history, medications, and the reason for testing.

Are there any risks?

The risks of this test are minimal and similar to routine blood draws. You may experience slight pain, bruising, or bleeding at the puncture site. In rare cases, fainting or infection may occur. These tests are generally very safe when performed by trained professionals.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How long do amphetamines stay in blood?
Amphetamines are typically detectable in blood for about 12-24 hours after use, though this varies depending on the specific drug, dosage, individual metabolism, and frequency of use. Methamphetamine may be detectable slightly longer than other amphetamines.
Can my prescription medications affect the test results?
Yes, certain prescription medications may cause false positive results. These include medications containing amphetamines (like Adderall, Vyvanse for ADHD, or medications for narcolepsy) and some antidepressants or cold medications. Always inform your doctor and the testing facility about all medications you are taking.
Will eating certain foods affect my test results?
Some foods contain compounds that may potentially cause false positives, though this is less common with blood tests than with urine tests. However, it is important to follow any fasting instructions provided by your healthcare provider.
Is this test the same as a workplace drug test?
This blood test is similar to the type of testing used in some workplace or forensic settings, though many organizations use urine or saliva tests instead. Blood tests are often more accurate and can detect drugs more recently after use.
What should I do if my test is positive?
If you test positive and have a valid prescription for an amphetamine medication, bring your prescription documentation to your healthcare provider or the testing facility. If you test positive unexpectedly or without a valid prescription, discuss the results with your doctor, who can provide appropriate guidance and referrals for treatment if needed.
  1. 1
    MedlinePlus - Amphetamine and Methamphetamine ScreenSource
  2. 2
    Mayo Clinic Laboratories - Amphetamines, SerumSource
  3. 3
    LabCorp - Amphetamines Confirmation, SerumSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy