Skip to content

Understanding Your Laboratory Test: A Patient's Guide to Testing, Results, and Follow-Up Care

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of amphetamine or methamphetamine in your blood to confirm previous screening results or monitor treatment.

Quick summary

{"A confirmatory test that accurately measures amphetamine levels in blood","Used to verify positive drug screening results or monitor medication levels","Sample is collected from a vein in your arm","Results help doctors understand if medication is being taken as prescribed","This test is more accurate than initial screening tests"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
82967-1
Short code
Amphet SerPlBld Cfm-mCnc
Synonyms
Amphet SerPlBld Cfm-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test, and why is it an important tool that healthcare providers use to evaluate your health and guide medical decisions?

The amphetamine confirmatory test measures the exact amount of amphetamine or methamphetamine in your blood. Unlike basic screening tests, this confirmatory method uses advanced laboratory techniques to provide highly accurate results. It is typically ordered after an initial positive screening test or when your healthcare provider needs to verify medication adherence.

Why do I need this test, and what can it tell my doctor about my symptoms, my overall health, or a condition I may have?

Your doctor may order this test for several reasons: to confirm the results of a previous screening test, to monitor amphetamine medication levels (such as for ADHD treatment), to check for medication compliance, or to evaluate symptoms that may be related to amphetamine use. This test is also used in substance abuse treatment programs and forensic settings when necessary.

How is this test performed, what should I expect during the appointment, and is there any special preparation I need to do beforehand?

A healthcare professional will draw a small blood sample from a vein in your arm using a needle. The blood will be collected in a special tube and sent to a laboratory for analysis. The test uses mass spectrometry, a highly sensitive technique that can precisely identify and measure the amount of amphetamine or methamphetamine in your blood.

Your results are compared against standard reference ranges to show whether your values fall within the normal range for healthy adults. Abnormal results do not always mean you have a serious condition, so your healthcare provider will review them with you, explain what they may indicate, and recommend any follow-up testing, monitoring, or treatment if needed.

Results are typically reported as positive or negative, and sometimes include the specific concentration level. A positive result means amphetamine or methamphetamine was detected in your blood. Your healthcare provider will interpret these results based on your medical history, the reason for testing, and any medications you are currently taking. Certain prescription medications and dietary supplements may affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This confirmatory test is clinically significant for verifying amphetamine use, monitoring therapeutic medication levels in patients prescribed amphetamines for ADHD or narcolepsy, assessing medication adherence, and distinguishing between intentional use and environmental exposure. It provides legally defensible results and helps guide treatment decisions in addiction medicine and psychiatric care.

Frequently asked questions

How long does amphetamine stay in blood?
Amphetamine can typically be detected in blood for about 24-48 hours after use, though this varies based on factors like metabolism, dosage, and individual physiology. Methamphetamine may be detectable for slightly longer.
Do I need to prepare for the test?
Your healthcare provider will give you specific instructions. Generally, you should inform them about all medications, supplements, and substances you have recently used. No fasting is typically required for this blood test.
Will my prescription ADHD medication show up on this test?
Yes, if you are taking prescribed amphetamine-based ADHD medication (such as Adderall), it will likely be detected. Always disclose your medications to your healthcare provider before testing.
How long will it take to get results?
Confirmatory tests typically take 2-5 days to process because they require specialized laboratory equipment and analysis. Your healthcare provider will contact you with results.
  1. 1
  2. 2

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy