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Amylase12hurcrate

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of amylase, a digestive enzyme, in your urine collected over 12 hours to evaluate pancreatic function.

Quick summary

{"Amylase is an enzyme produced by the pancreas that helps digest carbohydrates","The test helps diagnose pancreatic disorders such as pancreatitis","You will collect all urine passed over a 12-hour period","Elevated levels may indicate pancreatic inflammation or blockage"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17841-8
Short code
Amylase 12h Ur-cRate
Synonyms
Amylase 12h Ur-cRate
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

The 12-hour urine amylase test measures the amount of amylase in your urine. Amylase is a digestive enzyme produced primarily by the pancreas and salivary glands that helps break down carbohydrates in the food you eat. This test evaluates how well your pancreas is functioning by detecting abnormal amylase levels in urine.

How is the test performed?

You will be given a special container to collect all urine over a 12-hour period, typically overnight. It's important to: start the collection at a specific time, urinate into the container for the entire 12-hour period, keep the container refrigerated during collection, and return the complete sample to your healthcare provider as instructed.

What do the results mean?

Normal amylase levels vary by laboratory. Your doctor will interpret your results based on your specific situation. Elevated urine amylase levels may indicate pancreatic inflammation (pancreatitis), pancreatic duct obstruction, pancreatic cancer, or certain kidney diseases. Low levels may sometimes indicate chronic pancreatic disease or kidney problems.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Why do I need to collect urine for 12 hours?
A 12-hour collection provides a more accurate assessment of amylase levels than a single urine sample, as amylase excretion can vary throughout the day. This extended collection helps standardize the test and gives a better picture of your pancreatic function.
Does this test require fasting?
Generally, no fasting is required for a urine amylase test. However, your doctor may provide specific instructions. It's important to follow all pre-test instructions provided by your healthcare team.
Are there any risks with this test?
There are no significant risks associated with this test. It is a simple urine collection procedure. The main challenges are ensuring accurate 12-hour collection and proper sample preservation.
What can affect my test results?
Certain medications, kidney function, and other medical conditions can affect amylase levels. Inform your doctor about all medications you are taking. Urinary tract infections can also potentially affect results.
How long does it take to get results?
Results are typically available within 1-2 days after the sample reaches the laboratory. Your healthcare provider will contact you with the results and explain what they mean for your health.
  1. 1
    MedlinePlus - AmylaseSource
  2. 2
    Mayo Clinic Laboratories - Amylase, UrineSource
  3. 3
    ARUP Consult - AmylaseSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy