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Amylase18hurcrate

Published: August 9, 2026Updated: August 16, 2026

A urine test that measures amylase enzyme levels collected over 18 hours to help evaluate pancreatic function.

Quick summary

{"Amylase is an enzyme that helps digest carbohydrates, produced by the pancreas and salivary glands","The 18-hour urine collection helps doctors assess how well your pancreas is working","Abnormal results may indicate pancreatic inflammation, blockage, or other conditions","You will need to collect all urine produced over an 18-hour period","Certain medications and conditions may affect your test results"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
59001-8
Short code
Amylase 18h Ur-cRate
Synonyms
Amylase 18h Ur-cRate
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

The 18-hour urine amylase test measures the amount of amylase enzyme in your urine. Amylase is produced by the pancreas and salivary glands, and it helps your body break down carbohydrates. By measuring amylase levels in urine collected over 18 hours, doctors can assess how well your pancreas is functioning.

Why do I need this test?

Your doctor may order this test if you have symptoms of pancreatic problems, such as abdominal pain, nausea, vomiting, or unexplained weight loss. It helps diagnose conditions like pancreatitis (inflammation of the pancreas), pancreatic duct obstruction, or pancreatic insufficiency.

How do I prepare for the test?

Follow these steps for accurate results: 1) Your doctor may ask you to stop certain medications that can affect results, such as some blood pressure drugs or diuretics. 2) Drink adequate fluids unless otherwise instructed. 3) Avoid alcohol for 24 hours before and during collection. 4) Follow the specific collection instructions provided by your lab.

How is the collection done?

You will receive a special container from the lab. On the first day, urinate into the toilet when you wake up. Note the exact time. For the next 18 hours, collect all urine in the container provided. Keep the container refrigerated or in a cool place. At the end of the 18-hour period, urinate one last time and add it to the container. Return the container to the lab as instructed.

What do the results mean?

Normal amylase levels vary by laboratory. High urine amylase levels may indicate acute or chronic pancreatitis, pancreatic duct obstruction, pancreatic cancer, or kidney disease. Low levels may suggest chronic pancreatitis or pancreatic insufficiency. Your doctor will interpret your results based on your symptoms and other test findings.

Are there any risks?

This test carries minimal risks. You may experience minor discomfort from the collection process. Some people may have difficulty collecting urine for an extended period. If you have a urinary tract infection, let your doctor know as it may affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings2

Frequently asked questions

Will the test be painful?
No, the urine collection process is painless. You may feel some discomfort from having to collect urine over an extended period, but there is no physical pain involved in the test itself.
Can I exercise during the collection period?
Avoid strenuous exercise during the 18-hour collection period, as excessive physical activity can affect amylase levels. Light activities are generally acceptable. Ask your doctor for specific guidance.
What happens if I miss collecting some urine during the 18 hours?
If you miss any urine during the collection period, tell the lab staff when you return the sample. They may need to discard the sample and have you start a new collection. It is important to collect all urine produced during the designated time period for accurate results.
Do I need to fast before this test?
Fasting is not typically required for a urine amylase test. However, your doctor may ask you to avoid alcohol for 24 hours before the test. Follow any specific instructions provided by your healthcare provider.
How long does it take to get results?
Results are usually available within 1-3 days, depending on the laboratory. Your doctor's office will contact you with the results or discuss them at your follow-up appointment.
  1. 1
    MedlinePlus - Amylase TestSource
  2. 2
    Mayo Clinic - PancreatitisSource
  3. 3
    Lab Tests Online - Urine AmylaseSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy